Briot Karine
Service de rhumatologie, Université René Descartes Paris V, Hôpital Cochin, Paris (75).
Presse Med. 2006 Oct;35(10 Pt 2):1579-83. doi: 10.1016/s0755-4982(06)74854-0.
After osteoporotic fracture or low bone mineral density measurements, it is necessary to look for secondary causes of osteoporosis, such as drugs. Corticosteroids are the most common cause of drug-induced metabolic bone disease. Other drugs responsible for bone disease include: aromatase inhibitors, GnRH agonists, anticonvulsants, heparin, and L thyroxin at TSH-suppressive doses. Confirmation is required of data about neuroleptics and antivitamin K.
在发生骨质疏松性骨折或骨密度测量值较低后,有必要查找骨质疏松的继发原因,如药物。皮质类固醇是药物性代谢性骨病最常见的病因。其他导致骨病的药物包括:芳香化酶抑制剂、促性腺激素释放激素激动剂、抗惊厥药、肝素以及超生理剂量的左甲状腺素。关于抗精神病药物和抗维生素K的数据需要进一步证实。