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分娩第一产程中经皮穴位电刺激(TENS)镇痛的随机双盲安慰剂对照试验

Pain relief by applying transcutaneous electrical nerve stimulation (TENS) on acupuncture points during the first stage of labor: a randomized double-blind placebo-controlled trial.

作者信息

Chao An-Shine, Chao Angel, Wang Tzu-Hao, Chang Yu-Cheng, Peng Hsiu-Huei, Chang Shuenn-Dyh, Chao Anne, Chang Chee-Jen, Lai Chyong-Huey, Wong Alice M K

机构信息

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taiwan Department of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan Graduate Institute of Basic Medical Sciences, Chang Gung University, Taiwan Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.

出版信息

Pain. 2007 Feb;127(3):214-220. doi: 10.1016/j.pain.2006.08.016. Epub 2006 Oct 6.

Abstract

Transcutaneous electrical nerve stimulation (TENS) is one of the non-pharmacological means of pain relief for labor and delivery. We aimed to investigate the efficacy and safety of TENS on specific acupuncture points for reducing pain in the first stage of labor. In this double-blind, placebo-controlled trial, we randomly assigned healthy full-term parturients in active phase of first-stage labor to either TENS on four acupuncture points (Hegu [Li 4] and Sanyinjiao [Sp 6]) (n=52) or the TENS placebo (n=53). Visual analogue scale (VAS) was used to assess pain before and 30 and 60 min after treatment. The primary outcome was the rate of VAS score decrease 3 in each group. A questionnaire was given at 24h post-partum to evaluate the satisfaction of pain relieving method and the willingness to have the same treatment again. Mode of delivery and neonatal effect were measured as secondary outcome. One hundred women were eligible for analysis. TENS group experienced VAS score reduction 3 significantly more common than the TENS placebo group (31/50 [62%] vs 7/50 [14%], P<0.001). Willingness of using the same analgesic method for a future childbirth was also significantly different (TENS: 48/50 [96%] vs TENS placebo: 33/50 [66%], P<0.001). Operative delivery was increased in the TENS group (12/50 [24%] vs 4/50 [8%], P=0.05), but the neonatal outcomes were not different. The application of TENS on specific acupuncture points could be a non-invasive adjunct for pain relief in the first stage of labor.

摘要

经皮电刺激神经疗法(TENS)是分娩时缓解疼痛的非药物方法之一。我们旨在研究在特定穴位使用TENS减轻第一产程疼痛的有效性和安全性。在这项双盲、安慰剂对照试验中,我们将处于第一产程活跃期的健康足月产妇随机分为四穴位(合谷穴[LI4]和三阴交穴[SP6])TENS组(n = 52)或TENS安慰剂组(n = 53)。使用视觉模拟评分法(VAS)在治疗前、治疗后30分钟和60分钟评估疼痛程度。主要结局是每组VAS评分降低≥3分的比例。产后24小时发放问卷,评估疼痛缓解方法的满意度以及再次接受相同治疗的意愿。分娩方式和新生儿情况作为次要结局进行测量。100名女性符合分析条件。TENS组VAS评分降低≥3分的情况比TENS安慰剂组更为常见(31/50 [62%] 对7/50 [14%],P<0.001)。未来分娩时使用相同镇痛方法的意愿也存在显著差异(TENS组:48/50 [96%] 对TENS安慰剂组:33/50 [66%],P<0.001)。TENS组剖宫产率有所增加(12/50 [24%] 对4/50 [8%],P = 0.05),但新生儿结局无差异。在特定穴位应用TENS可能是第一产程疼痛缓解的一种非侵入性辅助方法。

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