Wickens Jason C, Shah Gaurav K
Washington University School of Medicine, St. Louis, Missouri, USA.
Retina. 2006 Oct;26(8):902-4. doi: 10.1097/01.iae.0000233338.56252.44.
Internal limiting membrane (ILM) peeling in macular hole surgery may allow a shortened period of face down positioning. This study reports the results of macular hole surgery combined with shortened (3-day) face down positioning.
The study was a retrospective review of data for 21 patients (21 eyes) treated for a macular hole by a single surgeon (G.K.S.). All patients underwent standard 3-port pars plana vitrectomy with triamcinolone-assisted ILM peeling and gas tamponade with 16% C3F8 or 25% SF6. Patients were instructed to remain in a face down position for 3 days at least 8 hours a day and to avoid flat on back positioning.
The main outcome of anatomical closure was achieved in 20 (95%) of 21 eyes. Snellen visual acuity improved >2 lines in 76% (16/21) of patients. No patient lost >1 line of Snellen visual acuity. Two patients had postoperative increased (>24 mmHg) intraocular pressure that was successfully treated with pressure-lowering drops. Initial surgery failed to achieve hole closure in one patient, but with a second surgery and similar face down positioning, the hole was closed.
This study found that macular hole surgery with ILM peeling and a shortened period of face down positioning achieves excellent anatomical closure and is not associated with significant adverse outcomes.
黄斑裂孔手术中剥除内界膜(ILM)可能允许缩短俯卧位的时间。本研究报告了黄斑裂孔手术联合缩短(3天)俯卧位的结果。
本研究是对由单一外科医生(G.K.S.)治疗的21例黄斑裂孔患者(21只眼)的数据进行的回顾性分析。所有患者均接受标准的三通道平坦部玻璃体切除术,术中使用曲安奈德辅助剥除ILM,并使用16%的C3F8或25%的SF6进行气体填充。患者被要求每天至少8小时保持俯卧位3天,并避免仰卧位。
21只眼中有20只(95%)实现了解剖学上的闭合这一主要结果。76%(16/21)的患者Snellen视力提高了2行以上。没有患者的Snellen视力下降超过1行。两名患者术后眼压升高(>24 mmHg),通过降眼压滴眼液成功治疗。一名患者初次手术未能实现裂孔闭合,但在二次手术及类似的俯卧位后,裂孔闭合。
本研究发现,剥除ILM并缩短俯卧位时间的黄斑裂孔手术可实现良好的解剖学闭合,且无显著不良后果。