Hasler P W, Prünte C
University Eye Clinic Basel, Switzerland.
Br J Ophthalmol. 2008 May;92(5):645-9. doi: 10.1136/bjo.2007.130971. Epub 2008 Feb 22.
To evaluate morphological and functional recovery after macular hole surgery using pars plana vitrectomy (PPV), inner limiting membrane (ILM) peeling, air-tamponade and short-time limited face-down positioning.
Retrospective, interventional, non-comparative consecutive case series.
Thirty eyes in 30 patients (30 eyes) with unilateral full-thickness macular hole (stage II-IV).
All eyes underwent PPV, ILM peeling and fluid-air exchange followed by postoperative face-down positioning for 2 days.
Best corrected visual acuity, optical coherence tomography (OCT) assessment of macular integrity, and biomicroscopy at days 3 and 7, and months 1, 3, 6 and 12.
On postoperative day 3, OCT demonstrated macular hole closure in 28 eyes (93%). One eye required vitrectomy 7 weeks after initial surgery due to retinal detachment.
In the present case series, PPV with Trypan Blue-assisted ILM peeling, short-acting internal tamponade and thus shorter face-down positioning was associated with a 93% macular hole closure rate.
评估采用玻璃体切除术（PPV）、内界膜（ILM）剥除术、空气填塞及短期有限俯卧位的黄斑裂孔手术后的形态和功能恢复情况。
回顾性、干预性、非对比性连续病例系列。
30例患者的30只眼（30眼），均为单侧全层黄斑裂孔（II-IV期）。
所有患眼均接受PPV、ILM剥除术及液气交换，术后俯卧位2天。
最佳矫正视力、黄斑完整性的光学相干断层扫描（OCT）评估，以及术后第3天和第7天、第1个月、第3个月、第6个月和第12个月的生物显微镜检查。
术后第3天，OCT显示28只眼（93%）黄斑裂孔闭合。1只眼因视网膜脱离在初次手术后7周需要再次行玻璃体切除术。
在本病例系列中，采用台盼蓝辅助ILM剥除术的PPV、短效内填塞以及因此缩短的俯卧位与93%的黄斑裂孔闭合率相关。
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