Profili Stefano, Manca Antonio, Feo Claudio F, Padua Guglielmo, Ortu Riccardo, Canalis Giulio C, Meloni Giovanni B
Department of Radiology, University of Sassari, Sassari, Italy.
Cardiovasc Intervent Radiol. 2007 Jan-Feb;30(1):74-8. doi: 10.1007/s00270-006-0027-6.
To assess the effectiveness of airway stenting performed exclusively under radiological guidance for the palliation of malignant tracheobronchial strictures.
We report our experience in 16 patients with malignant tracheobronchial stricture treated by insertion of 20 Ultraflex self-expandable metal stents performed under fluoroscopic guidance only. Three patients presented dysphagia grade IV due to esophageal malignant infiltration; they therefore underwent combined airway and esophageal stenting. All the procedures were performed under conscious sedation in the radiological room; average procedure time was around 10 min, but the airway impediment never lasted more than 40 sec.
We obtained an overall technical success in 16 cases (100%) and clinical success in 14 patients (88%). All prostheses were successfully placed without procedural complications. Rapid clinical improvement with symptom relief and normalization of respiratory function was obtained in 14 cases. Two patients died within 48 hr from causes unrelated to stent placement. Two cases (13%) of migration were observed; they were successfully treated with another stent. Tumor overgrowth developed in other 2 patients (13%); however, no further treatment was possible because of extensive laryngeal infiltration.
Tracheobronchial recanalization with self-expandable metal stents is a safe and effective palliative treatment for malignant strictures. Airway stenting performed exclusively under fluoroscopic view was rapid and well tolerated.
评估仅在放射学引导下进行气道支架置入术对缓解恶性气管支气管狭窄的有效性。
我们报告了16例恶性气管支气管狭窄患者的治疗经验,这些患者仅在透视引导下置入了20枚Ultraflex自膨式金属支架。3例患者因食管恶性浸润出现IV级吞咽困难,因此接受了气道和食管联合支架置入术。所有手术均在放射科清醒镇静下进行;平均手术时间约为10分钟,但气道阻塞时间从未超过40秒。
16例患者全部获得技术成功(100%),14例患者获得临床成功(88%)。所有假体均成功置入,无手术并发症。14例患者临床症状迅速改善,症状缓解,呼吸功能恢复正常。2例患者在48小时内死于与支架置入无关的原因。观察到2例(13%)支架移位,经再次置入支架成功治疗。另外2例患者(13%)出现肿瘤过度生长;然而,由于广泛的喉部浸润,无法进行进一步治疗。
自膨式金属支架置入气管支气管再通术是治疗恶性狭窄的一种安全有效的姑息治疗方法。仅在透视下进行气道支架置入术操作迅速,耐受性良好。