Oelschlager B K, Lal D R, Jensen E, Cahill M, Quiroga E, Pellegrini C A
The Swallowing Center and Department of Surgery, University of Washington, Seattle, WA, USA.
Surg Endosc. 2006 Dec;20(12):1817-23. doi: 10.1007/s00464-005-0262-y.
For a small subset of patients, laparoscopic fundoplication fails, typically resulting in recurrent reflux or severe dysphagia. Although redo fundoplications can be performed laparoscopically, few studies have examined their long-term efficacy.
Using a prospectively maintained database, the authors identified and contacted 41 patients who had undergone redo laparoscopic fundoplications at the University of Washington between 1996 and 2001. The median follow-up period was 50 months (range, 20-95 months). Current symptoms were compared with those acquired and entered into the authors' database preoperatively. Patients also were asked to return for esophageal manometry and pH testing.
All redo fundoplications were performed laparoscopically. There were no conversions. The most common indication for redo fundoplication was recurrent reflux. The most common anatomic abnormality was a herniated wrap. Heartburn improved in 61%, regurgitation in 69%, and dysphagia in 74% of the patients. Complete resolution of these symptoms was achieved, respectively, in 45%, 41% and 38% of these same patients. Overall, 68% of the patients rated the success of the procedure as either "excellent" or "good," and 78% said they were happy they chose to have it. For those who underwent reoperation for gastroesophageal reflux disease, distal esophageal acid exposure according to 24-h pH monitoring decreased after redo fundoplication from 15.7% +/- 18.1% to 3.4% +/- 3.6% (p = 0.041).
Although not as successful as primary fundoplication, a majority of patients can expect durable improvement in their symptoms with a laparoscopic redo fundoplication.
对于一小部分患者,腹腔镜胃底折叠术会失败,通常会导致反流复发或严重吞咽困难。尽管可以通过腹腔镜进行再次胃底折叠术,但很少有研究探讨其长期疗效。
作者利用一个前瞻性维护的数据库,识别并联系了1996年至2001年间在华盛顿大学接受再次腹腔镜胃底折叠术的41例患者。中位随访期为50个月(范围20 - 95个月)。将当前症状与术前获取并录入作者数据库的症状进行比较。患者还被要求返回进行食管测压和pH值测试。
所有再次胃底折叠术均通过腹腔镜完成。无中转开腹情况。再次胃底折叠术最常见的指征是反流复发。最常见的解剖异常是包绕疝出。61%的患者烧心症状改善,69%的患者反流症状改善,74%的患者吞咽困难症状改善。这些症状在相同患者中的完全缓解率分别为45%、41%和38%。总体而言,68%的患者将手术成功率评为“优秀”或“良好”,78%的患者表示很高兴选择了该手术。对于因胃食管反流病接受再次手术的患者,根据24小时pH值监测,再次胃底折叠术后食管远端酸暴露从15.7%±18.1%降至3.4%±3.6%(p = 0.041)。
尽管不如初次胃底折叠术成功,但大多数患者可预期通过腹腔镜再次胃底折叠术使症状得到持久改善。