溶液流速对2.5CaO x 2SiO₂玻璃体外生物活性的影响

Effect of the solution flow rate on the in vitro bioactivity of 2.5CaO x 2SiO(2) glass.

作者信息

Luciani G, Costantini A, Silvestri B, Cajafa M, Colella M, Branda F

机构信息

Dipartimento di Ingegneria dei Materiali e della Produzione, Piazzale Tecchio, 80-80125 Napoli, Italy.

出版信息

J Biomed Mater Res A. 2007 Mar 1;80(3):592-601. doi: 10.1002/jbm.a.30959.

DOI:10.1002/jbm.a.30959

PMID:17031823

Abstract

A comparative study of in vitro bioactivity of 2.5CaO x 2SiO(2) glass has been carried out by soaking it in a simulated body fluid, with continuously and periodic exchange of this solution (dynamic and differential protocols). Dynamic assays were carried out at different solution flow rates, 3 mL/h, 6 mL/h, 12 mL/h, to study the influence of flow rate on glass reactivity. Glass surface was studied by Fourier transform infrared spectroscopy, scanning electron microscopy, and energy dispersive spectroscopy so as to compare the behavior in the two procedures, revealing that in both cases an apatite layer is formed on the glass surface, although there are differences on deposition rate and morphology, which are also influenced by the solution flow rate.

摘要

通过将2.5CaO x 2SiO₂玻璃浸泡在模拟体液中，并持续定期更换该溶液（动态和差异方案），对其体外生物活性进行了比较研究。在不同的溶液流速（3 mL/h、6 mL/h、12 mL/h）下进行动态测定，以研究流速对玻璃反应性的影响。通过傅里叶变换红外光谱、扫描电子显微镜和能量色散光谱对玻璃表面进行了研究，以便比较两种程序中的行为，结果表明，在两种情况下，玻璃表面均形成了磷灰石层，尽管沉积速率和形态存在差异，且这些差异也受溶液流速的影响。