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韩国青少年和青年双胞胎敌意的非加性遗传效应

Nonadditive genetic effects on hostility in South Korean adolescent and young adult twins.

作者信息

Hur Yoon-Mi

机构信息

Institute of Reproductive Medicine and Population, Medical Research Center, Seoul National University, Seoul, South Korea.

出版信息

Twin Res Hum Genet. 2006 Oct;9(5):637-41. doi: 10.1375/183242706778553408.

Abstract

Hostility has been shown to be a vulnerability marker for various health problems. The present study examined genetic and environmental contributions to individual differences in hostility in South Korean adolescent and young adult twins. Seven hundred and nineteen same- and opposite-sex twin pairs aged from 13 to 23 years completed a hostility scale. The scalar sex-limitation model was applied to the data. The best fitting model indicated that 34% of the total variation of hostility was attributable to genetic factors operating in a nonadditive manner. The remaining 66% of the variance was associated with nonshared environmental influences and measurement error. These findings were largely consistent with results from previous twin studies of personality based on Caucasian twins, rendering support for the pervasive influence of genetic nonadditivity on human personality traits and the generalization of the heritability of personality across human populations.

摘要

敌意已被证明是各种健康问题的一个脆弱性指标。本研究调查了韩国青少年和青年双胞胎敌意个体差异的遗传和环境因素。719对年龄在13至23岁的同性和异性双胞胎完成了一份敌意量表。对数据应用了标量性别限制模型。最佳拟合模型表明,敌意总变异的34%可归因于以非加性方式起作用的遗传因素。其余66%的变异与非共享环境影响和测量误差有关。这些发现与之前基于白种人双胞胎的人格双胞胎研究结果基本一致,支持了遗传非加性对人类人格特质的普遍影响以及人格遗传性在不同人群中的普遍性。

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