Troelsen Lone N, Jacobsen Søren
H:S Rigshospitalet, Finsencentret, Reumatologisk Klinik 4242, København Ø.
Ugeskr Laeger. 2006 Sep 25;168(39):3304-8.
Rheumatoid arthritis is associated with increased cardiovascular morbidity and mortality due to atherosclerosis. This cannot be explained by an increased presence of traditional risk factors but seems to depend on inflammatory mechanisms. The association of inflammatory pathways with atherosclerosis is complex, and more research is required to optimise preventative measures against cardiovascular complications in inflammatory rheumatic diseases.
类风湿性关节炎与动脉粥样硬化导致的心血管发病率和死亡率增加有关。这无法用传统危险因素的增加来解释,而似乎取决于炎症机制。炎症途径与动脉粥样硬化之间的关联很复杂,需要更多研究来优化针对炎性风湿性疾病心血管并发症的预防措施。