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[Dementia--genetic aspects].

作者信息

Lindquist Suzanne Granhøj, Waldemar Gunhild, Nielsen Jørgen Erik

机构信息

H:S Rigshospitalet, Neurocentret, Neurologisk Klinik, H:S Hukommelsesklinikken.

出版信息

Ugeskr Laeger. 2006 Oct 2;168(40):3405-8.

Abstract

Several prevalent, sporadic neurodegenerative disorders also occur as rare inherited variants. Mapping of the genes involved in rare variants of the disorders has contributed to elucidating pathogenetic pathways for several dementia disorders, and the increased knowledge creates a possibility for development of new molecular genetic methods for diagnostics and for the treatment of the different types of dementia. Although inherited dementia disorders are generally rare, a genetic basis should always be considered when facing a patient with a recently clinically diagnosed dementia disorder.

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