Krasil'nikov O V
Nauchnye Doki Vyss Shkoly Biol Nauki. 1990(10):5-20.
A brief review is devoted to the results of the study of molecular mechanism interaction between membrane-active colicins and membranes in model systems. The data on physical-chemical properties of colicins most studied, the relationship between the structure and the properties of ion channels formed by them in membranes are given. The characteristics of such channels, the dependence of their functioning on the composition of aqueous medium and on transmembrane potential are discussed in detail. The hypotheses on the structure of colicin channels and experimental data concerning the size of their water pore ane considered.
本文简要回顾了在模型系统中对膜活性大肠杆菌素与膜之间分子机制相互作用的研究结果。给出了对研究最多的大肠杆菌素物理化学性质的数据，以及它们在膜中形成的离子通道的结构与性质之间的关系。详细讨论了此类通道的特性、其功能对水相介质组成和跨膜电位的依赖性。还考虑了关于大肠杆菌素通道结构的假说以及有关其水孔大小的实验数据。
