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1
Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls.肝移植受者从环孢素转换为基于FK 506的免疫抑制：益处与风险。
Transplant Proc. 1991 Feb;23(1 Pt 1):14-21.
2
Positive crossmatch in primary human liver allografts under cyclosporine or FK 506 therapy.在环孢素或FK 506治疗下原发性人肝同种异体移植中的阳性交叉配型
Transplant Proc. 1991 Feb;23(1 Pt 1):396-9.
3
Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications.肝移植受者中因环孢素相关并发症而从环孢素转换为FK506治疗。
Transplant Proc. 1990 Feb;22(1):6-12.
4
Efficiency of FK 506 and CyA to prevent acute cellular rejection of pig liver allografts.FK506和环孢素A预防猪肝同种异体移植急性细胞排斥反应的效率。
Transplant Proc. 1991 Aug;23(4):2233-5.
5
Conversion of liver allograft recipients from cyclosporine A to FK 506 immunosuppressive therapy.肝移植受者从环孢素A转换为FK506免疫抑制治疗。
Transplant Proc. 2000 Jun;32(4):709-10. doi: 10.1016/s0041-1345(00)00951-9.
6
A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection.一项关于环孢素、FK 506和雷帕霉素对同种异体移植排斥反应抑制作用的对比研究。
Transplant Proc. 1990 Aug;22(4):1638-41.
7
Pancreaticoduodenal allotransplantation with the use of FK 506, cyclosporine, and triple-regimen immunosuppression.使用FK 506、环孢素和三联免疫抑制方案进行胰十二指肠同种异体移植。
Transplant Proc. 1990 Aug;22(4):1655-7.
8
Comparison of short-term immunosuppressive therapy with cyclosporine and FK 506 in small-bowel transplantation.小肠移植中短期使用环孢素和FK 506进行免疫抑制治疗的比较。
Transplant Proc. 1990 Dec;22(6):2485-6.
9
FK 506 rescue therapy for intractable liver allograft rejection.FK506 挽救治疗难治性肝移植排斥反应。
Transpl Int. 1994;7 Suppl 1:S70-6. doi: 10.1111/j.1432-2277.1994.tb01313.x.
10
Prognostic factors for successful conversion from cyclosporine to FK 506-based immunosuppressive therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group.肝移植后难治性排斥反应从环孢素转换为基于FK 506的免疫抑制治疗成功的预后因素。美国多中心FK 506肝脏研究组。
Transplant Proc. 1993 Feb;25(1 Pt 1):641-3.

引用本文的文献

1
The Effect of Weight and CYP3A5 Genotype on the Population Pharmacokinetics of Tacrolimus in Stable Paediatric Renal Transplant Recipients.体重和CYP3A5基因分型对稳定期小儿肾移植受者他克莫司群体药代动力学的影响。
Clin Pharmacokinet. 2016 Sep;55(9):1129-43. doi: 10.1007/s40262-016-0390-7.
2
Enigmatic pruritus in a kidney transplant patient.一名肾移植患者的神秘瘙痒症
Clin Kidney J. 2013 Apr;6(2):194-8. doi: 10.1093/ckj/sft009.
3
Tacrolimus (FK506)-Associated Renal Pathology.他克莫司（FK506）相关的肾脏病理学。
Adv Anat Pathol. 1997 Jul;4(4):265-276. doi: 10.1097/00125480-199707000-00032.
4
Clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplantation.他克莫司在实体器官移植中的临床药代动力学与药效学
Clin Pharmacokinet. 2004;43(10):623-53. doi: 10.2165/00003088-200443100-00001.
5
Single-dose daclizumab induction therapy in patients with liver transplantation.肝移植患者的单剂量达克珠单抗诱导治疗。
World J Gastroenterol. 2003 Aug;9(8):1881-3. doi: 10.3748/wjg.v9.i8.1881.
6
Does tacrolimus offer virtual freedom from chronic rejection after primary liver transplantation? Risk and prognostic factors in 1,048 liver transplantations with a mean follow-up of 6 years.他克莫司能否为初次肝移植后的慢性排斥反应提供几乎完全的预防？1048例肝移植患者的风险及预后因素分析，平均随访6年。
Liver Transpl. 2001 Jul;7(7):623-30. doi: 10.1053/jlts.2001.25364.
7
Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs.在慢性肝移植排斥反应中，胆管上皮细胞的复制性衰老先于胆管丢失：p21（WAF1/Cip1）表达增加作为疾病标志物以及免疫抑制药物的影响。
Am J Pathol. 2001 Apr;158(4):1379-90. doi: 10.1016/S0002-9440(10)64089-8.
8
Immunosuppressive drugs in paediatric liver transplantation.儿童肝移植中的免疫抑制药物
Paediatr Drugs. 2001;3(1):43-60. doi: 10.2165/00128072-200103010-00004.
9
Comparative long-term evaluation of tacrolimus and cyclosporine in pediatric liver transplantation.他克莫司与环孢素在儿童肝移植中的长期比较评估。
Transplantation. 2000 Aug 27;70(4):617-25. doi: 10.1097/00007890-200008270-00015.
10
Chronic liver allograft rejection in a population treated primarily with tacrolimus as baseline immunosuppression: long-term follow-up and evaluation of features for histopathological staging.在以他克莫司作为基础免疫抑制进行主要治疗的人群中慢性肝移植排斥反应：长期随访及组织病理学分期特征评估
Transplantation. 2000 Jun 15;69(11):2330-6. doi: 10.1097/00007890-200006150-00019.

本文引用的文献

1
Studies on the mechanism of action of cyclosporin A.环孢素A作用机制的研究。
Immunobiology. 1980 Jan;156(4-5):454-63. doi: 10.1016/S0171-2985(80)80078-7.
2
The refolding of urea-denatured ribonuclease A is catalyzed by peptidyl-prolyl cis-trans isomerase.肽基脯氨酰顺反异构酶催化尿素变性的核糖核酸酶A的重折叠。
Biochim Biophys Acta. 1985 Mar 22;828(1):39-42. doi: 10.1016/0167-4838(85)90006-8.
3
Isolation and amino acid sequence of cyclophilin.亲环蛋白的分离与氨基酸序列
J Biol Chem. 1986 Jun 25;261(18):8547-55.
4
Cyclosporine.环孢素
N Engl J Med. 1989 Dec 21;321(25):1725-38. doi: 10.1056/NEJM198912213212507.
5
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase.免疫抑制剂FK506的一种受体是一种顺反肽基脯氨酰异构酶。
Nature. 1989 Oct 26;341(6244):758-60. doi: 10.1038/341758a0.
6
FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.FK-506，一种从链霉菌中分离出的新型免疫抑制剂。II. FK-506的体外免疫抑制作用。
J Antibiot (Tokyo). 1987 Sep;40(9):1256-65. doi: 10.7164/antibiotics.40.1256.
7
A highly sensitive method to assay FK-506 levels in plasma.一种检测血浆中FK-506水平的高灵敏度方法。
Transplant Proc. 1987 Oct;19(5 Suppl 6):23-9.
8
Transplantation.移植
JAMA. 1990 May 16;263(19):2686-7.
9
Liver, kidney, and thoracic organ transplantation under FK 506.在使用FK506情况下的肝脏、肾脏及胸部器官移植。
Ann Surg. 1990 Sep;212(3):295-305; discussion 306-7. doi: 10.1097/00000658-199009000-00008.
10
Suppression of allograft rejection with FK506. I. Prolonged cardiac and liver survival in rats following short-course therapy.用FK506抑制同种异体移植排斥反应。I. 短期治疗后大鼠心脏和肝脏存活时间延长
Transplantation. 1990 Aug;50(2):186-9. doi: 10.1097/00007890-199008000-00002.

Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls.

作者信息

Fung J J, Todo S, Tzakis A, Demetris A, Jain A, Abu-Elmaged K, Alessiani M, Starzl T E

机构信息

Department of Surgery, University of Pittsburgh School of Medicine, Pennsylvania 15213.

出版信息

Transplant Proc. 1991 Feb;23(1 Pt 1):14-21.

PMID:1703682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2954599/
Abstract
摘要