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Use of rapamycin for the suppression of alloimmune reactions in vivo: schedule dependence, tolerance induction, synergy with cyclosporine and FK 506, and effect on host-versus-graft and graft-versus-host reactions.

作者信息

Morris R E, Meiser B M, Wu J, Shorthouse R, Wang J

机构信息

Department of Cardiovascular Surgery, Stanford University, School of Medicine, California 94305-5247.

出版信息

Transplant Proc. 1991 Feb;23(1 Pt 1):521-4.

PMID:1703698
Abstract
摘要

相似文献

1
Use of rapamycin for the suppression of alloimmune reactions in vivo: schedule dependence, tolerance induction, synergy with cyclosporine and FK 506, and effect on host-versus-graft and graft-versus-host reactions.
Transplant Proc. 1991 Feb;23(1 Pt 1):521-4.
2
A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection.一项关于环孢素、FK 506和雷帕霉素对同种异体移植排斥反应抑制作用的对比研究。
Transplant Proc. 1990 Aug;22(4):1638-41.
3
Synergistic interactions of cyclosporine, rapamycin, and brequinar on heart allograft survival in mice.环孢素、雷帕霉素和布喹那对小鼠心脏同种异体移植存活的协同相互作用。
Transplant Proc. 1994 Oct;26(5):3025-7.
4
Immunopharmacology of FK-506.FK-506的免疫药理学
Transplant Proc. 1989 Feb;21(1 Pt 1):1042-4.
5
Rapamycin suppression of host-versus-graft and graft-versus-host disease in MHC-mismatched rats.
Transplant Proc. 1992 Jun;24(3):1174.
6
Comparative study of toxicity and efficacy of cyclosporine, cyclosporine G (OG37), FK 506, and rapamycin in BALB/c mice with fitted skin grafts.
Transplant Proc. 1995 Feb;27(1):366.
7
Effect of FK 506 and cyclosporine on heart allograft survival in rats.FK506和环孢素对大鼠心脏同种异体移植存活的影响。
Transplant Proc. 1991 Feb;23(1 Pt 1):529-30.
8
Prolongation by rapamycin of heart, kidney, pancreas, and small bowel allograft survival in rats.雷帕霉素延长大鼠心脏、肾脏、胰腺和小肠同种异体移植的存活时间。
Transplant Proc. 1991 Feb;23(1 Pt 1):507-8.
9
Inhibition of skin graft rejection in mice by rapamycin: a novel immunosuppressive macrolide.雷帕霉素对小鼠皮肤移植排斥反应的抑制作用：一种新型免疫抑制大环内酯类药物。
Transplant Proc. 1991 Feb;23(1 Pt 1):868-9.
10
Rapamycin and cyclosporine synergistically prolong heart and kidney allograft survival.雷帕霉素和环孢素协同延长心脏和肾脏同种异体移植的存活时间。
Transplant Proc. 1991 Dec;23(6):3262-4.

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The evaluation of potential pharmacokinetic interaction between sirolimus and tacrolimus in healthy volunteers.
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4
Rapamycin inhibits re-endothelialization after percutaneous coronary intervention by impeding the proliferation and migration of endothelial cells and inducing apoptosis of endothelial progenitor cells.雷帕霉素通过阻碍内皮细胞的增殖和迁移以及诱导内皮祖细胞凋亡，抑制经皮冠状动脉介入术后的再内皮化。
Tex Heart Inst J. 2010;37(2):194-201.
5
New immunosuppressive drugs: mechanistic insights and potential therapeutic advances.新型免疫抑制药物：作用机制洞察与潜在治疗进展
Immunol Rev. 1993 Dec;136:71-98. doi: 10.1111/j.1600-065x.1993.tb00655.x.
6
The changing face of liver transplantation.肝移植不断变化的面貌。
Gut. 1993 Mar;34(3):295-8. doi: 10.1136/gut.34.3.295.
7
Efficacy of rapamycin and FK 506 in prolonging rat hind limb allograft survival.雷帕霉素和FK 506在延长大鼠后肢同种异体移植存活时间方面的疗效。
Ann Surg. 1994 Jan;219(1):88-93. doi: 10.1097/00000658-199401000-00014.
8
Rapamycin prevents the onset of insulin-dependent diabetes mellitus (IDDM) in NOD mice.雷帕霉素可预防非肥胖型糖尿病（NOD）小鼠胰岛素依赖型糖尿病（IDDM）的发病。
Clin Exp Immunol. 1992 Aug;89(2):174-8. doi: 10.1111/j.1365-2249.1992.tb06928.x.
9
Optimisation of immunosuppressive therapy using pharmacokinetic principles.
Clin Pharmacokinet. 1992 Nov;23(5):380-90. doi: 10.2165/00003088-199223050-00004.