Heermann J, Candas H
Laryngol Rhinol Otol (Stuttg). 1977 Mar;56(3):273-6.
An up-to-eight-hour lasting anterograde amnesia is achieved by "Rohypnol" i.v. causing no excitation before local anesthesia is given (prolongation by analgetics, anesthetics, neuroleptics). The cardiovascular functions remain stable with spontaneous breathing and preservation of the swallow and coughing reflexes. During the operation the patient is responsive and cooperative. The patient answers all questions, moves his body into any wanted position and when ordered he performs Valsalva's manoeuver without any remembrane. If not spoken to and having no pain he falls asleep right away. Postoperative vomiting is reduced. The patient feels relaxed after waking up. No complications have been noticed during more than 500 operations. The later questioning of all patients showed only 4 patients (with unsufficient preoperative sedation) who could remember part of the terminal phase of the operation.
静脉注射“罗眠乐”可产生长达八小时的顺行性遗忘,在给予局部麻醉前不会引起兴奋(镇痛药、麻醉药、抗精神病药可延长其作用时间)。心血管功能保持稳定,自主呼吸正常,吞咽和咳嗽反射得以保留。手术过程中患者反应灵敏且配合良好。患者能回答所有问题,将身体移动到任何所需位置,按指令进行瓦尔萨尔瓦动作时毫无记忆。若无人与他交谈且无疼痛,他会立即入睡。术后呕吐减少。患者醒来后感觉轻松。在500多次手术中未发现并发症。对所有患者术后随访发现,只有4名患者(术前镇静不足)能回忆起手术末期的部分情况。