Neofytos Dionissios, Pfaller Michael A, Diekema Daniel J, Horn David
Division of Infectious Diseases and Environmental Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Mycopathologia. 2006 Oct;162(4):295-8. doi: 10.1007/s11046-006-0060-7.
Candida species is the fourth most commonly isolated organism in blood stream infections in the hospital setting. Patients with candidemia frequently succumb to this infection. For those that survive an initial candidemia, an increasing number of cases of breakthrough or recurrent candidemias have been reported in the literature. We report three episodes of C. parapsilosis fungemia in a cancer patient. Molecular testing was performed and confirmed that all these episodes occurring within an eight-month period were caused by the same organism. The incidence of recurrent candidemia is likely to increase in the near future. Studies and therapeutic interventions for patients at risk for recurrent candidemias are warranted.
念珠菌属是医院环境中血流感染中第四常见的分离出的微生物。念珠菌血症患者常死于这种感染。对于那些在初次念珠菌血症中存活下来的患者,文献中报道的突破性或复发性念珠菌血症病例越来越多。我们报告了一名癌症患者发生的三例近平滑念珠菌真菌血症。进行了分子检测,证实这八 个月内发生的所有这些病例均由同一微生物引起。复发性念珠菌血症的发病率在不久的将来可能会增加。有必要对有复发性念珠菌血症风险的患者进行研究和治疗干预。