Pulmonary benign metastasizing leiomyoma: a report of 2 cases with different outcomes.

作者信息

Benetti-Pinto Cristina Laguna, Soares Patrícia Magda, Petta Carlos Alberto, De Angelo-Andrade Liliana A L

机构信息

Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas, Campinas, Brazil.

出版信息

J Reprod Med. 2006 Sep;51(9):715-8.

BACKGROUND

Benign metastasizing leiomyoma (BML) of the lung is a rare manifestation of metastasis from a uterine myoma, in which its benign characteristics are maintained. The majority of cases are asymptomatic.

CASES

Case 1 responded to the classic treatment of oophorectomy, after which an improvement in symptoms was achieved. In case 2, however, symptoms appeared following oophorectomy and were treated with raloxifene.

CONCLUSION

These cases show the uncertainty that exists with respect to the evolution and treatment of symptomatic BML. Raloxifene is a therapeutic agent that has not been widely studied for this purpose but should be considered for inclusion in the arsenal of therapeutic options available.