Fischer Robert J
Department of Obstetrics and Gynecology, 1st Fighter Wing Hospital/SGOBO, 45 Pine Street, Langley Air Force Base, VA 23665-2025, USA.
J Reprod Med. 2006 Sep;51(9):742-4.
Extrauterine lesions of intermediate trophoblast have occurred in and around fallopian tubes and ovaries and are thought to result from an exaggerated trophoblastic response to the implantation site of a previous ectopic pregnancy. Additionally, cesarean scar defects have recently been identified as a source of persistent, irregular vaginal bleeding in women and can be identified by pelvic ultrasound.
A 35-year-old woman presented with irregular vaginal bleeding in association with an anterior extrauterine cystic mass detected by pelvic ultrasound and thought to represent a cesarean scar defect. Subsequent histology revealed an endometrial diverticulum lined with chorionic-type intermediate trophoblast, a subpopulation of trophoblast that composes placental site nodules.
This was the first case of a lesion of intermediate trophoblast occurring in a cesarean scar diverticulum.