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哺乳动物阶段血吸虫中的葡萄糖转运与代谢

Glucose Transport and Metabolism in Mammalian-stage Schistosomes.

作者信息

Skelly P J, Tielens A G, Shoemaker C B

机构信息

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

出版信息

Parasitol Today. 1998 Oct;14(10):402-6. doi: 10.1016/s0169-4758(98)01319-2.

DOI:10.1016/s0169-4758(98)01319-2
PMID:17040830
Abstract

Adult schistosomes transport nutrients from the host bloodstream across their outer body covering or tegument. The tegument is a cytologically unusual structure; it is a syncytium bounded externally by two lipid bilayer membranes. In this review, Patrick Skelly, Louis Tielens and Chuck Shoemaker reconsider our understanding of how glucose enters schistosomes across this unusual outer covering in the light of recent papers characterizing glucose transport proteins and glucose metabolism pathways in these parasites.

摘要

成年血吸虫从宿主血液中摄取营养物质,并通过其体表外层或皮层进行运输。皮层是一种细胞学上独特的结构;它是一个合胞体,外部由两层脂质双分子膜界定。在这篇综述中,帕特里克·斯凯利、路易斯·蒂伦斯和查克·休梅克根据最近几篇描述这些寄生虫中葡萄糖转运蛋白和葡萄糖代谢途径的论文,重新审视了我们对于葡萄糖如何穿过这种独特的外层结构进入血吸虫的理解。

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