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前列腺癌高剂量率组织间近距离治疗的新型门诊植入技术

New ambulatory implant technique of high-dose-rate interstitial brachytherapy for prostate cancer.

作者信息

Yoshida Ken, Nose Takayuki, Shiomi Hiroya, Yoshioka Yasuo, Fujita Yuka, Kuroda Satoru, Yoshida Mineo, Takahashi Tohru, Kitamura Masaya, Akai Hideyuki, Oka Toshitsugu, Hosoki Takuya

机构信息

Department of Radiology, Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka 540-0006, Japan.

出版信息

Radiat Med. 2006 Oct;24(8):595-9. doi: 10.1007/s11604-007-0058-1.

DOI:10.1007/s11604-007-0058-1
PMID:17041799
Abstract

PURPOSE

The aim of this study was to improve the performance status of prostate cancer patients during high-dose-rate interstitial brachytherapy (HDR-ISBT). To this end, we have developed a new ambulatory implant technique.

MATERIALS AND METHODS

Ten prostate cancer patients were treated with HDR-ISBT as monotherapy from October 2003 until March 2004. We utilized a new removable template, a flexible applicator with a nonmetallic bead and button stopper, and an inner catheter connecting the applicator and the transfer tube of the brachytherapy unit. We shortened the connector end of the flexible applicator to enable the patient to sit down and walk freely during the treatment time.

RESULTS

All 10 patients could walk without any support. No problem in the application was observed.

CONCLUSION

Our new ambulatory implant technique for HDR-ISBT was able to improve the performance status of prostate cancer patients.

摘要

目的

本研究旨在改善前列腺癌患者在高剂量率组织间近距离放疗(HDR-ISBT)期间的身体机能状态。为此,我们开发了一种新的门诊植入技术。

材料与方法

2003年10月至2004年3月,10例前列腺癌患者接受了HDR-ISBT单一疗法治疗。我们使用了一种新型可移除模板、带有非金属珠和纽扣塞的柔性施源器,以及连接施源器与近距离放疗设备传输管的内导管。我们缩短了柔性施源器的连接端,以使患者在治疗期间能够自由坐下和行走。

结果

所有10例患者均可无需任何支撑行走。未观察到应用过程中的问题。

结论

我们新的HDR-ISBT门诊植入技术能够改善前列腺癌患者的身体机能状态。

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Clinical results of combined treatment conformal high-dose-rate iridium-192 brachytherapy and external beam radiotherapy using staging lymphadenectomy for localized prostate cancer.使用分期淋巴结清扫术联合适形高剂量率铱-192近距离放射治疗和外照射放疗对局限性前列腺癌进行综合治疗的临床结果。
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High-dose-rate brachytherapy as monotherapy for prostate cancer: technique, rationale and perspective.高剂量率近距离放射疗法作为前列腺癌的单一疗法:技术、原理与展望
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Current status and perspectives of brachytherapy for prostate cancer.前列腺癌近距离治疗的现状与展望
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Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue.
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Needle displacement during HDR brachytherapy in the treatment of prostate cancer.高剂量率近距离放射治疗前列腺癌时的针移位
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