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高剂量率近距离放射疗法作为前列腺癌的单一疗法:技术、原理与展望

High-dose-rate brachytherapy as monotherapy for prostate cancer: technique, rationale and perspective.

作者信息

Yoshioka Yasuo, Suzuki Osamu, Otani Yuki, Yoshida Ken, Nose Takayuki, Ogawa Kazuhiko

机构信息

Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka, Japan.

Department of Radiology, Osaka Medical College, Osaka, Japan.

出版信息

J Contemp Brachytherapy. 2014 Mar;6(1):91-8. doi: 10.5114/jcb.2014.42026. Epub 2014 Apr 3.

DOI:10.5114/jcb.2014.42026
PMID:24790627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4003433/
Abstract

High-dose-rate (HDR) brachytherapy as monotherapy is a comparatively new brachytherapy procedure for prostate cancer. Although clinical results are not yet mature enough, it is a highly promising approach in terms of potential benefits for both radiation physics and radiobiology. In this article, we describe our technique for monotherapeutic HDR prostate brachytherapy, as well as the rationale and theoretical background, with educational intent.

摘要

高剂量率(HDR)近距离放射疗法作为单一疗法是一种相对较新的前列腺癌近距离放射治疗方法。尽管临床结果尚未足够成熟,但就放射物理学和放射生物学的潜在益处而言,它是一种极具前景的方法。在本文中,我们出于教学目的描述了单一疗法HDR前列腺近距离放射治疗的技术,以及其原理和理论背景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa52/4003433/6e75a3714386/JCB-6-22585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa52/4003433/3f753094d484/JCB-6-22585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa52/4003433/3b3633bfa5c7/JCB-6-22585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa52/4003433/6e75a3714386/JCB-6-22585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa52/4003433/3f753094d484/JCB-6-22585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa52/4003433/3b3633bfa5c7/JCB-6-22585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa52/4003433/6e75a3714386/JCB-6-22585-g003.jpg

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J Contemp Brachytherapy. 2013 Dec;5(4):203-9. doi: 10.5114/jcb.2013.38657. Epub 2013 Oct 31.
2
High-dose-rate brachytherapy alone given as two or one fraction to patients for locally advanced prostate cancer: acute toxicity.高剂量率近距离放射治疗单独给予局部晚期前列腺癌患者,分两次或一次进行:急性毒性反应
Radiother Oncol. 2014 Feb;110(2):268-71. doi: 10.1016/j.radonc.2013.09.025. Epub 2013 Nov 11.
3
Monotherapeutic high-dose-rate brachytherapy for prostate cancer: a dose reduction trial.
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Multi-needle Localization with Attention U-Net in US-guided HDR Prostate Brachytherapy.基于超声引导高剂量率前列腺近距离治疗的多针定位与注意力 U-Net。
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