Halim A S, Imran Y
Reconstructive Science Unit, Department of Surgery, Universiti Sains Malaysia, Kubang Kerian.
Med J Malaysia. 2006 Feb;61 Suppl A:66-70.
Post-traumatic chronic osteomyelitis and infected non-unions of the tibia following severe type-III open fracture are difficult to treat Refractoy cases often necessitate amputation despite attempts to salvage the limb. We report our experience in treating such difficult cases with an alternative surgical option using free osteocutaneous fibular graft. Eight consecutive patients with post-traumatic chronic osteomyelitis/infected non-union were treated surgically with free vascularized osteocutaneous fibular graft. Outcomes in term of graft-host union and complication were evaluated. Four patients had anastomotic venous thrombosis requiring anastomotic revision. Five patients developed surgical site infections needing extended antibiotic therapy to achieve resolution at an average of 15.2 weeks. Fibular graft fracture occurred in three patients but all grafts survived and united after a mean time to union of 42.3 weeks (range 31 to 82 weeks). At the final follow-up, union of host-graft junction and control of infection were achieved in all patients except one who required a secondary amputation. Free vascularized osteo-cutaneous fibular graft is a viable limb salvage option for refractory chronic osteomyelitis or infected non-union following treatment of grade-III open tibial fractures.
严重Ⅲ型开放性胫骨骨折后创伤后慢性骨髓炎和感染性骨不连难以治疗。尽管尝试保肢,但难治性病例往往需要截肢。我们报告了使用游离腓骨骨皮瓣这种替代手术方法治疗此类疑难病例的经验。连续8例创伤后慢性骨髓炎/感染性骨不连患者接受了游离带血管腓骨骨皮瓣手术治疗。评估了移植物与宿主骨愈合及并发症方面的结果。4例患者发生吻合口静脉血栓形成,需要进行吻合口修复。5例患者出现手术部位感染,需要延长抗生素治疗,平均15.2周后感染得到控制。3例患者发生腓骨移植骨骨折,但所有移植物均存活,平均42.3周(31至82周)后愈合。在最后一次随访时,除1例需要二次截肢的患者外,所有患者均实现了宿主与移植物结合处的愈合及感染控制。游离带血管腓骨骨皮瓣是治疗Ⅲ型开放性胫骨骨折后难治性慢性骨髓炎或感染性骨不连的一种可行的保肢选择。