Szepietowski Jacek C, Reich Adam, Garlowska Emilia, Kulig Marzena, Baran Eugeniusz
Mycologic Section of the Polish Dermatological Society, Department of Dermatology, Venereology, and Allergology, University of Medicine, Wroclaw, Poland.
Arch Dermatol. 2006 Oct;142(10):1279-84. doi: 10.1001/archderm.142.10.1279.
To evaluate the prevalence and factors influencing the presence of concomitant dermatomycoses in patients with toenail onychomycosis.
Prospective study based on a specially designed questionnaire completed by dermatologists.
A total of 2761 patients with toenail onychomycosis.
The diagnosis of fungal skin infections was confirmed by direct microscopic examination or by culture.
In 1181 patients (42.8%) with toenail onychomycosis, concomitant fungal skin infections were noted. Tinea pedis was the most common and was found in 933 patients (33.8%). Other concomitant fungal skin infections were fingernail onychomycosis (7.4%), tinea cruris (4.2%), tinea corporis (2.1%), tinea manuum (1.6%), and tinea capitis (0.5%). The presence of concomitant fungal skin infections depended on number of involved toenails; duration of onychomycosis; sex, age, and education level; area of residence; and type of isolated fungus.
The coexistence of toenail onychomycosis with other types of fungal skin infections is a frequent phenomenon. It could be hypothesized that infected toenails may be a site from which the fungal infections could spread to other body areas. Effective therapy for onychomycosis might therefore be essential not only to treat the lesional toenails but also to prevent spreading the infection to other sites of the skin.
评估趾甲甲真菌病患者合并皮肤癣菌病的患病率及影响因素。
基于皮肤科医生填写的专门设计问卷的前瞻性研究。
共2761例趾甲甲真菌病患者。
通过直接显微镜检查或培养确诊真菌性皮肤感染。
1181例（42.8%）趾甲甲真菌病患者合并有真菌性皮肤感染。足癣最为常见，933例（33.8%）患者存在足癣。其他合并的真菌性皮肤感染包括指甲甲真菌病（7.4%）、股癣（4.2%）、体癣（2.1%）、手癣（1.6%）和头癣（0.5%）。合并真菌性皮肤感染的情况取决于受累趾甲的数量、甲真菌病的病程、性别、年龄和教育水平、居住地区以及分离出的真菌类型。
趾甲甲真菌病与其他类型真菌性皮肤感染并存是一种常见现象。可以推测，感染的趾甲可能是真菌感染扩散到身体其他部位的源头。因此，有效的甲真菌病治疗不仅对于治疗受累趾甲至关重要，而且对于防止感染扩散到皮肤其他部位也必不可少。
