[尿素指甲油对指甲质量的影响。临床评估和生物物理测量]
[Effect of urea nail lacquer on nail quality. Clinical evaluation and biophysical measurements].
作者信息
Krüger N, Reuther T, Williams S, Kerscher M
机构信息
Studiengang Kosmetik und Körperpflege, Department Chemie, Universität Hamburg, Martin-Luther-King Platz 6, 20146 Hamburg.
出版信息
Hautarzt. 2006 Dec;57(12):1089-94. doi: 10.1007/s00105-006-1215-7.
BACKGROUND
Urea is a well-known humectant. The aim of our study was to evaluate the in vivo effect of 10% urea lacquer on nail quality.
METHODS
60 healthy probands with brittle nails were included in a randomized, controlled study. The nail lacquer was applied once (n=30) or twice daily (n=30) on one hand for 28 days, while the other hand served as untreated control. Assessments included clinical evaluations and bioengineering measurements.
RESULTS
Application of the nail lacquer was well-tolerated and led to a significant clinical improvement of nail surface morphology, nail plate consistency, reflection of the nail plate surface, appearance of the cuticle and the nail fold. Sonographic nail density was slightly increased. No relevant changes were found in nail thickness and transonychial water loss.
CONCLUSIONS
Nail lacquer containing urea improves the cosmetic appearance of fingernails.
背景
尿素是一种广为人知的保湿剂。我们研究的目的是评估10%尿素指甲油对指甲质量的体内效果。
方法
60名患有脆甲症的健康受试者被纳入一项随机对照研究。指甲油在一只手上每天涂抹一次（n=30）或两次（n=30），持续28天，而另一只手作为未处理的对照。评估包括临床评估和生物工程测量。
结果
指甲油的使用耐受性良好，并导致指甲表面形态、甲板一致性、甲板表面反射、角质层和甲襞外观有显著的临床改善。超声测量的指甲密度略有增加。指甲厚度和经甲水分流失未发现相关变化。
结论
含尿素的指甲油可改善指甲的外观。
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