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泰国成年人群中慢性肾脏病的患病率。

Prevalence of chronic kidney disease in Thai adult population.

作者信息

Chittinandana Anutra, Chailimpamontree Worawon, Chaloeiphap Preecha

机构信息

Renal Division, Department of Medicine, Bhumibol Adulyadej Hospital, Royal Thai Air Force, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2006 Aug;89 Suppl 2:S112-20.

Abstract

OBJECTIVE

Chronic kidney disease (CKD) is a major public health problem worldwide. Until now, no large-scale data about the prevalence of pre-dialysis CKD has been reported in Thailand.

MATERIAL AND METHOD

The clinical and laboratory data from the ground air force personnel who were routinely checked up during 2002-2003 were collected and descriptively analyzed. The pilots and air crews were excluded. All personnel were working in Bangkok.

RESULTS

15,612 RTAF personnel completed the annual check up. Eighty-two percent were male. The average age was 45.7 +/- 8 (19-65) years. According to the classification of stages of CKD by Kidney Disease Outcome Quality Initiative (K/DOQI), the prevalence of CKD is 9.1% by Cockcroft Gault formula and 4.6% by Modification of Diet in Renal Disease. Patients with diabetes mellitus, hypertension, hypercholesterolemia and proteinuria were found in 8.2%, 45.8 %, 28.2 % and 1.8% respectively. CKD patients were older had higher body weight, Body Mass Index (BMI), blood pressure and blood sugar than non CKD personnel.

CONCLUSION

CKD were not uncommon among RTAF personnel. The Cockcroft-Gault and MDRD equations were different in detecting CKD in the present study. The appropriate equation to determine GFR in Thai population should be evaluated. Low sensitivity of dipstick proteinuria may cause the low prevalence of stage 1 and 2 CKD.

摘要

目的

慢性肾脏病(CKD)是全球主要的公共卫生问题。迄今为止,泰国尚未有关于透析前CKD患病率的大规模数据报道。

材料与方法

收集2002年至2003年期间接受定期体检的地面空军人员的临床和实验室数据,并进行描述性分析。飞行员和空勤人员被排除在外。所有人员均在曼谷工作。

结果

15612名皇家泰国空军人员完成了年度体检。其中82%为男性。平均年龄为45.7±8(19 - 65)岁。根据肾脏病预后质量倡议(K/DOQI)的CKD分期分类,通过Cockcroft Gault公式计算的CKD患病率为9.1%,通过肾脏病饮食改良公式计算为4.6%。分别有8.2%、45.8%、28.2%和1.8%的人员患有糖尿病、高血压、高胆固醇血症和蛋白尿。CKD患者比非CKD人员年龄更大,体重、体重指数(BMI)、血压和血糖更高。

结论

CKD在皇家泰国空军人员中并不罕见。在本研究中,Cockcroft - Gault和MDRD方程在检测CKD方面存在差异。应评估适用于泰国人群的估算肾小球滤过率(GFR)的合适方程。试纸法蛋白尿的低敏感性可能导致1期和2期CKD的低患病率。

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