Dlugos Dennis J
Division of Neurology, Children's Hospital of Philadelphia, Department of Neurology and Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
Epilepsia. 2006;47 Suppl 1:54-7. doi: 10.1111/j.1528-1167.2006.00661.x.
Presented is the case of a child with epilepsy with dramatic evolution between the ages of 18 months and 3 years. Initially, the case is one of treatment-responsive focal epilepsy, but then evolves to treatment-resistant focal epilepsy with an epileptic encephalopathy. The case demonstrates the poorly understood entities of age-related changes in seizure suspectibility, seizure types, and drug responsiveness.
本文介绍了一名癫痫患儿的病例，该患儿在18个月至3岁之间病情急剧演变。最初，该病例属于治疗反应性局灶性癫痫，但随后演变为伴有癫痫性脑病的治疗抵抗性局灶性癫痫。该病例表明，人们对癫痫易感性、癫痫发作类型和药物反应性中与年龄相关的变化这些尚不十分了解的情况。
