Krainick-Strobel Ute, Majer Ina, Huber Birte, Gall Christian, Krämer Bernhard, Gruber Ines, Fehm Tanja, Huober Jens, Hierlemann Helmut, Doser Michael, Meyberg-Solomayer Gabriele, Hoffmann Jürgen, Wallwiener Diethelm, Hahn Markus
Department of Gynaecology and Obstetrics, Breast Centre, University of Tuebingen, Tuebingen, Germany.
Ultrasound Med Biol. 2006 Oct;32(10):1539-44. doi: 10.1016/j.ultrasmedbio.2006.06.016.
In combination with high-resolution ultrasound (US), vacuum-assisted biopsy (VB) techniques can be used for accurate diagnosis confirmation and therapeutic minimally invasive removal of benign breast lesions. We developed a gel-simulation model to imitate the removal of benign breast lesions (e.g., fibroadenoma) with VB from a turkey breast-phantom. Bilobular US-sensitive models in the form of a fibroadenoma were manufactured from flexible, cuttable synthetic material (longitudinal diameters of 4-20 mm). They were implanted in turkey meat and vacuum biopsied under 2-D and 3-D imaging with 11G and 8 G needles. The minimum number of cylinders removed per tumour volume, the maximum complete excision tumour size and the optimum needle gauge were determined. Lesions with a longitudinal diameter of up to 10 to 12 mm could be removed with the 11G needle, those up to 20 mm with the 8G needle. The values for the correct needle size, number of cylinders per tumour size to be removed produced with the gel turkey phantoms provide a reference for clinicians performing VB with total excision intent. VB is suitable for the removal of benign lesions with a diameter of up to 20 mm.
结合高分辨率超声（US），真空辅助活检（VB）技术可用于准确确诊以及对良性乳腺病变进行微创治疗性切除。我们开发了一种凝胶模拟模型，以模拟用VB从火鸡胸模拟物中切除良性乳腺病变（如纤维腺瘤）的过程。以纤维腺瘤形式存在的双叶型超声敏感模型由可切割的柔性合成材料制成（纵向直径为4 - 20毫米）。将它们植入火鸡肉中，并在二维和三维成像下用11G和8G针进行真空活检。确定了每单位肿瘤体积切除的最小圆柱数量、最大完全切除肿瘤大小以及最佳针径。纵向直径达10至12毫米的病变可用11G针切除，达20毫米的病变可用8G针切除。凝胶火鸡模拟物得出的正确针径值以及每单位肿瘤大小要切除的圆柱数量，为有完全切除意向进行VB的临床医生提供了参考。VB适用于切除直径达20毫米的良性病变。
