Sánchez Alvarado Alejandro, Tsonis Panagiotis A
Howard Hughes Medical Institute, University of Utah School of Medicine, Deptartment of Neurobiology and Anatomy, Salt Lake City, Utah 84132, USA.
Nat Rev Genet. 2006 Nov;7(11):873-84. doi: 10.1038/nrg1923.
Significant progress has recently been made in our understanding of animal regenerative biology, spurred on by the use of a wider range of model organisms and an increasing ability to use genetic tools in traditional models of regeneration. This progress has begun to delineate differences and similarities in the regenerative capabilities and mechanisms among diverse animal species, and to address some of the key questions about the molecular and cell biology of regeneration. Our expanding knowledge in these areas not only provides insights into animal biology in general, but also has important implications for regenerative medicine and stem-cell biology.
最近，在我们对动物再生生物学的理解方面取得了重大进展，这得益于使用了更广泛的模式生物，以及在传统再生模型中使用基因工具的能力不断提高。这一进展已开始描绘不同动物物种在再生能力和机制方面的差异与相似之处，并解决一些有关再生的分子和细胞生物学的关键问题。我们在这些领域不断扩展的知识不仅为一般动物生物学提供了见解，也对再生医学和干细胞生物学具有重要意义。
