Kiatpongsan Sorapop, Mutirangura Apiwat, Tannirandorn Yuen
Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, Thailand.
J Med Assoc Thai. 2006 Aug;89(8):1322-32.
Cancer has been proposed as a result of abnormal control of growth and development of stem cells for more than century. This is the "cancer stem cell hypothesis". Both cancer and stem cells share many common especial properties. They are immortal and have good differentiation potential. In addition, organogenesis and carcinogenesis are very similar processes. Recently, more evidence and convincing data from stem cell biology research are supporting this concept. Furthermore, the research provides new promising approaches for cancer diagnosis and treatment based on stem cell knowledge and technology. Upcoming data and evidence may revolutionize cancer management, making it more effective and safer.
一个多世纪以来,癌症一直被认为是干细胞生长和发育异常控制的结果。这就是“癌症干细胞假说”。癌症和干细胞都具有许多共同的特殊性质。它们是永生的,并且具有良好的分化潜能。此外,器官发生和癌变是非常相似的过程。最近,干细胞生物学研究的更多证据和令人信服的数据支持了这一概念。此外,该研究基于干细胞知识和技术为癌症诊断和治疗提供了新的有前景的方法。即将到来的数据和证据可能会彻底改变癌症治疗,使其更有效、更安全。