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乳酸乳球菌菌株中吸附抑制、限制/修饰和流产感染型噬菌体抗性系统的鉴定。

Identification of adsorption inhibition, restriction/modification and abortive infection type phage resistance systems in Lactococcus lactis strains.

作者信息

Tükel Cağla, Sanlibaba Pinar, Ozden Banu, Akçelik M

机构信息

Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, One Shields Avenue, Davis, CA 95616-8645, USA.

出版信息

Acta Biol Hung. 2006 Sep;57(3):377-85. doi: 10.1556/ABiol.57.2006.3.11.

Abstract

98 Lactococcus lactis strains were isolated from traditional fermented milk products in Turkey tested against 60 lactococcal lytic phages to determine their resistance levels. While 82 L. lactis strains were sensitive against lactic phages at different levels, 16 L. lactis strains showed resistance to all phages tested. Types of phage resistance among 16 L. lactis strains were identified as phage adsorption inhibition in eight strains, restriction/modification in six strains and abortive infection (heat sensitive phage resistance) in two strains, using three broad-spectrum phages phi pll 98-32, phi pld 67-42 and phi pld 67-44.

摘要

从土耳其传统发酵乳制品中分离出98株乳酸乳球菌菌株,针对60株乳球菌裂解性噬菌体进行测试,以确定它们的抗性水平。虽然82株乳酸乳球菌菌株对不同水平的乳酸噬菌体敏感,但16株乳酸乳球菌菌株对所有测试噬菌体均表现出抗性。使用三种广谱噬菌体phi pll 98-32、phi pld 67-42和phi pld 67-44,确定16株乳酸乳球菌菌株中的噬菌体抗性类型,其中8株为噬菌体吸附抑制,6株为限制/修饰,2株为流产感染(热敏感噬菌体抗性)。

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