在生物系统中产生双相信号响应的调节模块。
Regulatory modules that generate biphasic signal response in biological systems.
作者信息
Levchenko A, Bruck J, Sternberg P W
机构信息
Whitaker Institute for Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
出版信息
Syst Biol (Stevenage). 2004 Jun;1(1):139-48. doi: 10.1049/sb:20045014.
Biochemical networks might be composed of modules. It is still not clear how biochemical modules can be defined and characterised. Here we propose a functional approach to module definition, considering different classes of biphasic regulation modules, which effect optimal cell response to intermediate signal strength. Each regulation class might possess unique properties that make it especially suitable for particular biological functions.
生化网络可能由模块组成。目前仍不清楚生化模块如何定义和表征。在此，我们提出一种功能方法来定义模块，考虑不同类别的双相调节模块，这些模块能使细胞对中等信号强度产生最佳反应。每个调节类别可能具有独特的特性，使其特别适合特定的生物学功能。
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