Del Giudice P, Ferraro V, Passeron A, Durant J, Bernard E, Choquenet N, Bouverot N, Lacour J P, Dellamonica P, Counillon E
Unité de Maladies Infectieuses et de Dermatologie, Hôpital Bonnet, Fréjus, Cedex, France.
Ann Dermatol Venereol. 2006 Aug-Sep;133(8-9 Pt 1):653-6. doi: 10.1016/s0151-9638(06)70986-3.
Since 2000, syphilis has reappeared in the form of an epidemic in France and more particularly, in the Paris region. However, there is little available data concerning other regions of France. The purpose of this study was to identify the chief characteristics of this epidemic in the Côte d'Azur region.
Between January 2001 and July 2003, cases of syphilis were collated by the Department of Dermatology and Infectious Diseases of Nice University Teaching Hospital and by the Department of Dermatology and Infectious Diseases of Fréjus hospital and based on spontaneous reports submitted by general practitioners in private practice.
We collected 54 reports of cases of syphilis: 37 in the Alpes-Maritimes region and 17 in the eastern Var region. The epidemic chiefly affected men since 44 of the 54 cases reported (81%) concerned males. 70% of these men were contaminated during homosexual contact (31 patients). In the majority of cases, contamination concerned local subjects. 50% of the patients in the study were infected with human immunodeficiency virus (HIV). The clinical forms observed were distributed as follows: 12 primary syphilis, 28 secondary syphilis, 13 latent syphilis, 1 case not specified. There was no difference in terms of clinical form between patients with and without HIV.
Syphilis, which had become rare in France as a whole and in our region in particular, reappeared in the form of an epidemic in the Côte d'Azur region after first resurfacing in the Paris region. This outbreak principally affected homosexual and bisexual male patients, half of whom were HIV-positive. Screening for syphilis, potentially latent, should thus be carried out routinely during initial assessment and at subsequent monitoring of HIV patients.
自2000年以来，梅毒在法国，尤其是巴黎地区再度以流行形式出现。然而，关于法国其他地区的可用数据很少。本研究的目的是确定蔚蓝海岸地区这一流行病的主要特征。
2001年1月至2003年7月期间，尼斯大学教学医院皮肤科和传染病科以及弗雷瑞斯医院皮肤科和传染病科根据私人执业全科医生提交的自发报告，对梅毒病例进行了整理。
我们收集到54例梅毒病例报告：滨海阿尔卑斯省有37例，瓦尔省东部有17例。该流行病主要影响男性，因为在报告的54例病例中有44例（81%）为男性。这些男性中有70%在同性恋接触期间感染（31例患者）。在大多数情况下，感染涉及当地居民。研究中的患者有50%感染了人类免疫缺陷病毒（HIV）。观察到的临床类型分布如下：一期梅毒12例，二期梅毒28例，潜伏梅毒13例，1例未明确分类。感染HIV和未感染HIV的患者在临床类型方面没有差异。
梅毒在法国整体尤其是我们所在地区曾变得罕见，在巴黎地区首次再度出现后，又在蔚蓝海岸地区以流行形式再现。此次疫情主要影响同性恋和双性恋男性患者，其中一半为HIV阳性。因此，在对HIV患者进行初始评估和后续监测时，应常规进行潜在潜伏梅毒的筛查。
