Lacour Sandrine A, de Monte Michèle, Diot Patrice, Brocca Jérôme, Veron Nadège, Colin Patrice, Leblond Valérie
Inserm, U618, Tours, F-37000 France.
BMC Public Health. 2006 Oct 20;6:261. doi: 10.1186/1471-2458-6-261.
PAPRICA is a research program designed to estimate the impact on the health of patients with chronic respiratory insufficiency of a prevention strategy based on notification of ozone pollution. The first year of this study was conducted during the 2003 heat wave, and high temperatures were therefore considered as a confounding factor in the data analysis. The aim of the present study was to assess the relationship between ozone and temperature in order to propose a methodology to distinguish between the effects of ozone and temperature on the impact of a prevention strategy with regard to ozone pollution.
Multivariate analyses were used to identify associated climate and ozone pollution profiles. This descriptive method is of great value to highlight the complexity of interactions between these parameters.
Ozone concentration and temperature were strongly correlated, but the health impact of ozone pollution alone will be evaluated by focusing on situations characterized by ozone concentrations above 110 mug/m3/8h (air quality guidelines to protect human health defined by the French legislation) and temperatures lower than 26 degrees C, below the discomfort threshold.
The precise relationship between ambient ozone concentration and temperature identified during the PAPRICA 2003 study period will be used in analysing the PAPRICA health data.
PAPRICA是一项研究项目,旨在评估基于臭氧污染通报的预防策略对慢性呼吸功能不全患者健康的影响。本研究的第一年在2003年热浪期间进行,因此高温被视为数据分析中的一个混杂因素。本研究的目的是评估臭氧与温度之间的关系,以便提出一种方法,区分臭氧和温度对臭氧污染预防策略影响的作用。
采用多变量分析来确定相关的气候和臭氧污染特征。这种描述性方法对于突出这些参数之间相互作用的复杂性具有重要价值。
臭氧浓度与温度密切相关,但仅关注臭氧浓度高于110微克/立方米/8小时(法国立法规定的保护人类健康的空气质量指南)且温度低于26摄氏度(不适阈值以下)的情况,来评估单独臭氧污染对健康的影响。
2003年PAPRICA研究期间确定的环境臭氧浓度与温度之间的确切关系将用于分析PAPRICA健康数据。