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[胰腺实性假乳头状瘤9例临床分析并文献复习]

[Clinical analysis of 9 cases of solid-cystic pseudopapillary tumor of the pancreas with literature review].

作者信息

Wang Zheng, Ma Qing-Yong, Liu Qing-Guang, Yao Ying-Min

机构信息

Department of Hepatobiliary Surgery, The First Affiliated Hospital, Medical College, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, P. R. China.

出版信息

Ai Zheng. 2006 Oct;25(10):1287-90.

Abstract

BACKGROUND & OBJECTIVE: Solid-cystic pseudopapillary tumor of the pancreas (SCPT) is a rare type of pancreatic tumor with low grade of malignancy. Its diagnosis and treatment remain controversial. This study was to discuss the diagnosis criteria and treatment strategy of SCPT.

METHODS

Clinical data, including general history, medical history, treatment history and treatment outcome, of 9 SCPT patients, treated in the Department of Hepatobiliary Surgery of the First Affiliated Hospital of Xi'an Jiaotong University from Jan. 1997 to Feb. 2005, were analyzed retrospectively, and the related literature was reviewed to summarize the clinical characteristics, diagnosis, and treatment of SCPT.

RESULTS

Among the 9 patients, 7 (77.8%) were women under 44 years old. The laboratory tests of liver function, serum amylase, and CEA, CA199 were normal. The accurate diagnosis rate of ultrasound was 22.2%, while that of CT was 77.8%. Most patients received local resection of the tumor. All patients were followed-up till Oct. 2005 and no metastasis was detected.

CONCLUSIONS

SCPT is a rare disease with good prognosis. It occurs mainly in young women. In spite of unspecific laboratory tests, CT and fine needle aspiration method are useful to diagnose the disease. Based on literatures, operation could achieve satisfactory efficacy for SCPT patients.

摘要

背景与目的

胰腺实性假乳头状瘤(SCPT)是一种罕见的胰腺肿瘤,恶性程度低。其诊断和治疗仍存在争议。本研究旨在探讨SCPT的诊断标准和治疗策略。

方法

回顾性分析1997年1月至2005年2月在西安交通大学第一附属医院肝胆外科治疗的9例SCPT患者的临床资料,包括一般病史、既往史、治疗史及治疗结果,并复习相关文献,总结SCPT的临床特点、诊断及治疗方法。

结果

9例患者中,7例(77.8%)为44岁以下女性。肝功能、血清淀粉酶、癌胚抗原(CEA)、糖类抗原199(CA199)等实验室检查均正常。超声检查的准确诊断率为22.2%,CT检查的准确诊断率为77.8%。大多数患者接受了肿瘤局部切除术。所有患者随访至2005年10月,均未发现转移。

结论

SCPT是一种罕见疾病,预后良好。主要发生于年轻女性。尽管实验室检查无特异性,但CT和细针穿刺方法有助于诊断该病。根据文献,手术治疗对SCPT患者可取得满意疗效。

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