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离心式血泵滑动轴承中径向间隙和转子运动对溶血的影响。

Influence of radial clearance and rotor motion to hemolysis in a journal bearing of a centrifugal blood pump.

作者信息

Kataoka Hiroyuki, Kimura Yuichi, Fujita Hajime, Takatani Setsuo

机构信息

Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

Artif Organs. 2006 Nov;30(11):841-54. doi: 10.1111/j.1525-1594.2006.00311.x.

Abstract

Hemolysis due to narrow clearance of noncontact bearings is a critical problem for rotary blood pumps. We developed a centrifugal blood pump with a magnetic and hydrodynamic hybrid bearing, and found that the hemolysis in the narrow clearance depends not only on the clearance size, but also on the rotor stability. In this study, we quantified the relation between the hemolysis, radial clearance (c), and rotor stability through the measurement of the rotor motion and hemolysis. As a result, it was confirmed that the rotor of the current pump is stabilized within the oscillation of 20 microm in blood, and the hemolysis decreases with increase in the c, which is the opposite in the unstable rotor motion with the previous pump. In order to theoretically discuss this hemolysis tendency, we implemented hemolysis estimation in the c according to hydrodynamics and hemodynamics. This estimation can represent the measured hemolysis tendency, and revealed that the flow rate has large influence on the hemolysis in the c.

摘要

非接触式轴承间隙狭窄导致的溶血是旋转血泵的一个关键问题。我们开发了一种带有磁流体动力混合轴承的离心血泵,并发现狭窄间隙中的溶血不仅取决于间隙大小,还取决于转子稳定性。在本研究中,我们通过测量转子运动和溶血来量化溶血、径向间隙(c)和转子稳定性之间的关系。结果证实,当前泵的转子在血液中20微米的振荡范围内稳定,溶血随c的增加而降低,这与之前泵的转子不稳定运动情况相反。为了从理论上讨论这种溶血趋势,我们根据流体动力学和血液动力学对c中的溶血进行了估计。该估计能够体现实测的溶血趋势,并揭示流速对c中的溶血有很大影响。

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