用于浅表真菌感染实验室诊断的荧光增白剂、氢氧化钾及培养法的比较
A comparison of calcofluor white, potassium hydroxide, and culture for the laboratory diagnosis of superficial fungal infection.
作者信息
Haldane D J, Robart E
机构信息
Department of Microbiology, Victoria General Hospital, Halifax, Nova Scotia, Canada.
出版信息
Diagn Microbiol Infect Dis. 1990 Jul-Aug;13(4):337-9. doi: 10.1016/0732-8893(90)90027-s.
A total of 207 skin scrapings were prospectively studied using potassium hydroxide (KOH), calcofluor white (CW), and culture to determine the clinical usefulness of each microscopic method. For dermatophytes (prevalence 13.2%), CW had a sensitivity of 92% and a specificity 95%, giving a positive predictive value of 74% and negative predictive value of 99%. KOH had a sensitivity of 88% and a specificity of 95%, giving a positive predictive value of 73% and a negative predictive value of 98%. CW was simple, rapid, and easy to read. For dermatophyte infection, CW results are as useful as KOH results.
前瞻性地对总共207份皮肤刮屑样本使用氢氧化钾（KOH）、荧光增白剂（CW）和培养法进行研究，以确定每种显微镜检查方法的临床实用性。对于皮肤癣菌（患病率13.2%），CW的敏感性为92%，特异性为95%，阳性预测值为74%，阴性预测值为99%。KOH的敏感性为88%，特异性为95%，阳性预测值为73%，阴性预测值为98%。CW操作简单、快速且易于判读。对于皮肤癣菌感染，CW的检测结果与KOH的结果同样有用。
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