Liepsch Dieter
Institut for Biotechnik, Munich University of Applied Sciences, Technical University of Munich, Munich, Germany.
Technol Health Care. 2006;14(4-5):209-14.
Biofluid mechanics is a complex field that focuses on blood flow and the circulation. Clinical applications include bypass and anastomosis surgery, and the development of artificial heart valves and vessels, stents, vein and dialysis shunts. Biofluid mechanics is also involved in diagnostic and therapeutic measures, including CT and MRI, and ultrasound. The study of biofluid mechanics involves measuring blood flow, pressure, pulse wave, velocity distribution, the elasticity of the vessel wall, the flow behavior of blood to minimize complications in vessel,- neuro-, and heart surgery. Biofluid mechanics influence the lungs and circulatory system, the blood flow and micro-circulation; lymph flow, and artificial organs. Flow studies in arterial models can be done without invasive techniques on patients or animals. The results of fluid mechanic studies have shown that in the addition to basic biology, an understanding of the forces and movement on the cells is essential. Because biofluid mechanics allows for the detection of the smallest flow changes, it has an enormous potential for future cell research. Some of these will be discussed.
生物流体力学是一个复杂的领域，专注于血流和循环。临床应用包括搭桥和吻合手术，以及人工心脏瓣膜和血管、支架、静脉和透析分流器的研发。生物流体力学还涉及诊断和治疗措施，包括CT、MRI和超声。生物流体力学的研究包括测量血流、压力、脉搏波、速度分布、血管壁弹性、血液流动行为，以尽量减少血管、神经和心脏手术中的并发症。生物流体力学影响肺部和循环系统、血流和微循环；淋巴流动以及人工器官。动脉模型中的血流研究可以在不采用侵入性技术的情况下对患者或动物进行。流体力学研究结果表明，除了基础生物学之外，了解细胞上的力和运动至关重要。由于生物流体力学能够检测到最小的血流变化，它在未来细胞研究方面具有巨大潜力。其中一些将进行讨论。
