Yoon Yong-Jin, Puria Sunil, Steele C R
Stanford University, Durand Building, Stanford, CA 94305-4035, USA.
ORL J Otorhinolaryngol Relat Spec. 2006;68(6):365-72. doi: 10.1159/000095279. Epub 2006 Oct 26.
Intracochlear pressure and basilar membrane (BM) velocity are calculated from a physiologically based chinchilla cochlea model . The model includes three-dimensional viscous fluid and the pectinate zone of the elastic BM with dimensional and material property variation along its length. The passive response shows excellent agreement with measurement at high sound pressure levels. The active process is represented by adding the motility of the outer hair cells (OHCs) to the passive model with the feed-forward approximation of the organ of Corti (OC), as was done previously. The current model explains recent observations including: (1) agreement with characteristic frequency (CF)-to-place map, (2) CF shift in the active model, (3) BM displacement gain from OHC motility, (4) lower intracochlear pressure gain than BM displacement gain, and (5) OC impedance (Z(OC)).
通过基于生理的灰鼠耳蜗模型计算耳蜗内压力和基底膜（BM）速度。该模型包括三维粘性流体和弹性基底膜的栉状区，其尺寸和材料特性沿其长度变化。被动响应在高声压水平下与测量结果显示出极好的一致性。如之前所做的那样，通过将外毛细胞（OHC）的能动性添加到具有柯蒂氏器（OC）前馈近似的被动模型中来表示主动过程。当前模型解释了最近的观察结果，包括：（1）与特征频率（CF）-位置图的一致性，（2）主动模型中的CF偏移，（3）OHC能动性导致的BM位移增益，（4）耳蜗内压力增益低于BM位移增益，以及（5）OC阻抗（Z(OC)）。
