Plaseska D, Wilson J B, Kutlar F, Font L, Baiget M, Huisman T H
Department of Cell and Molecular Biology, Medical College of Georgia, Augusta 30912-2100.
Hemoglobin. 1990;14(5):511-6. doi: 10.3109/03630269009005804.
Hb F-Catalonia, a G gamma chain variant with a Trp----Arg substitution at position gamma 15(A12), was observed in two Spanish newborn babies from Northeastern Spain. Analyses were performed with different reversed phase high performance liquid chromatographic procedures that allowed the identification of the amino acid replacement in only a minute quantity of the isolated G gamma X chain.
血红蛋白F-加泰罗尼亚型,一种γ链变体,在γ15(A12)位置存在色氨酸到精氨酸的替换,在两名来自西班牙东北部的新生儿中被发现。使用不同的反相高效液相色谱法进行分析,这些方法能够仅从微量分离出的GγX链中鉴定出氨基酸替换。