Noseda G
Schweiz Med Wochenschr. 1975 Sep 27;105(39):1233-7.
Hypolipidemias can be divided in primary, familial and hereditary forms and symptomatic forms which may accompany other diseases. The primary hypolipidemias (abetalipoproteinemia, hypobetalipoproteinemia and analphalipoproteinemia) are very rare. Severe hypolipidemia can be found in some peoples (e.g. the Masai). This article is chiefly devoted to secondary hypolipidemias such as those associated with malabsorption, malnutrition and maldigestion including protein-losing gastroenteropathy, with liver diseases, endocrine diseases (hyperthyroidism, hirsutism) and anemia. Finally, the hypolipidemias secondary to the formation of autoantibodies against HDL and LDL in M-gradient, carcinoma and rheumatoid arthritis are briefly reviewed.
低脂血症可分为原发性、家族性和遗传性形式以及可能伴随其他疾病的症状性形式。原发性低脂血症(无β脂蛋白血症、低β脂蛋白血症和无α脂蛋白血症)非常罕见。在一些人群(如马赛人)中可发现严重低脂血症。本文主要关注继发性低脂血症,如与吸收不良、营养不良和消化障碍(包括蛋白丢失性胃肠病)、肝脏疾病、内分泌疾病(甲状腺功能亢进、多毛症)及贫血相关的低脂血症。最后,简要综述了在M梯度、癌症和类风湿关节炎中因针对高密度脂蛋白和低密度脂蛋白产生自身抗体而继发的低脂血症。