García-Morales Irene, Pérez-Gil Amalia, Camacho Francisco M
Departamento de Dermatología, Hospital Universitario Virgen Macarena, Sevilla. España.
Actas Dermosifiliogr. 2006 Oct;97(8):529-32. doi: 10.1016/s0001-7310(06)73457-3.
The term Marjolin's ulcer means the malignant transformation of chronic ulcers, sinus tract and burn scars. The most frequently produced neoplasm is squamous cell carcinoma. The pathogeny is unknown, involving mutations in the Fas gene. Main therapeutic management are consist of prophylactic measures, avoiding repeated traumas and prolonged cure periods. We present the case of a 48-year-old male with squamous cell carcinoma on the old burn scar of legs that evolved favorably after excision.
马乔林溃疡一词指的是慢性溃疡、窦道和烧伤瘢痕的恶性转化。最常发生的肿瘤是鳞状细胞癌。其发病机制尚不清楚，涉及Fas基因的突变。主要治疗措施包括预防措施，避免反复创伤和延长治愈期。我们报告一例48岁男性，其腿部陈旧烧伤瘢痕处发生鳞状细胞癌，切除后病情好转。
