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[急性丙型肝炎病毒感染——临床表现、诊断与治疗]

[Acute hepatitis C virus infection--clinical manifestations, diagnosis and treatment].

作者信息

Peters Lars, Lindhardt Bjarne Ørskov

机构信息

H:S Rigshospitalet, Epidemiklinikken M 5132, København Ø.

出版信息

Ugeskr Laeger. 2006 Oct 16;168(42):3601-4.

Abstract

Acute infection with hepatitis C virus (HCV) usually runs a mild or asymptomatic course and therefore often goes undiagnosed. In the individual patient, acute hepatitis C (AHC) cannot clinically be distinguished from other forms of viral hepatitis. The diagnosis is based on rising serum alanine aminotransferase level, anti-HCV IgG seroconversion and detection of HCV-RNA in serum. In recent years there has been an increase in our understanding of the natural course of AHC, and progress has been made in its treatment. In this article we describe the clinical manifestations and diagnosis of AHC and review recent developments in its treatment.

摘要

丙型肝炎病毒(HCV)急性感染通常病程轻微或无症状,因此常常未被诊断出来。对于个体患者,急性丙型肝炎(AHC)在临床上无法与其他形式的病毒性肝炎相区分。诊断基于血清丙氨酸氨基转移酶水平升高、抗-HCV IgG血清学转换以及血清中HCV-RNA的检测。近年来,我们对AHC自然病程的认识有所增加,其治疗也取得了进展。在本文中,我们描述了AHC的临床表现和诊断,并综述了其治疗的最新进展。

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