镰状细胞贫血患儿日间脉搏血氧饱和度读数低与夜间血氧饱和度下降及阻塞性睡眠呼吸暂停有关。
Low daytime pulse oximetry reading is associated with nocturnal desaturation and obstructive sleep apnea in children with sickle cell anemia.
作者信息
Spivey John F, Uong Elizabeth C, Strunk Robert, Boslaugh Sarah E, DeBaun Michael R
机构信息
Department of Pediatrics, Washington University School of Medicine/St. Louis Children's Hospital, St. Louis, Missouri, USA.
出版信息
Pediatr Blood Cancer. 2008 Feb;50(2):359-62. doi: 10.1002/pbc.21054.
Abstract
A retrospective medical record review was established to test the hypothesis that in children with sickle cell anemia (SCA), a daytime oxygen saturation (SpO(2)) </=94% is associated with nocturnal desaturation with or without obstructive sleep apnea (OSA). Twenty children had a resting SpO(2) </=94% and an abnormal polysomnogram (PSG). Seven patients had OSA and thirteen patients had nocturnal desaturation. The average daytime SpO(2) correlated with the average nighttime SpO(2) (Spearman correlation coefficient = 0.453; P = 0.045). Our results indicate that in children with SCA, a daytime SpO(2) </=94% is a reasonable threshold to recommend a pulmonary evaluation, including a PSG.
摘要
开展了一项回顾性病历审查，以检验以下假设：在镰状细胞贫血（SCA）患儿中，白天血氧饱和度（SpO₂）≤94%与伴或不伴阻塞性睡眠呼吸暂停（OSA）的夜间血氧饱和度下降相关。20名患儿静息SpO₂≤94%且多导睡眠图（PSG）异常。7例患者有OSA，13例患者有夜间血氧饱和度下降。平均白天SpO₂与平均夜间SpO₂相关（Spearman相关系数=0.453；P=0.045）。我们的结果表明，在SCA患儿中，白天SpO₂≤94%是推荐进行包括PSG在内的肺部评估的合理阈值。
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