Lam Liza, Bilek Jaromir, Atkinson John
University of Southampton, Highfield, Southampton, SO17 1BJ, UK.
IEEE Trans Biomed Eng. 2006 Nov;53(11):2341-6. doi: 10.1109/TBME.2006.879466.
The partial pressures of gases, namely oxygen and carbon dioxide, in the arterial blood are important parameters for doctors to determine the respiratory conditions of patients. Currently in practice, there are a number of ways to measure these parameters, one of which is transcutaneous blood gas monitoring. This technique is a popular noninvasive measurement method for obtaining fast and relatively accurate responses. In this investigation, thick film technology has been employed to develop an amperometric oxygen sensor which consists of a heating module to elevate the temperature at the skin surface to transcutaneous levels. The heating module includes a heating element and its temperature is regulated by a temperature control circuit. Using an infrared camera, the transient and steady-state temperature distributions as well as the stability of the heating element have been analysed. The influence of temperature on the oxygen sensing module is also studied. In addition, a three-dimensional theoretical model is established to evaluate the thermal response of the sensor and subsequently compared with the results from the practical prototype. With this model, the design stages can be simplified and future heating modules for transcutaneous sensors could be generated and improved more easily and effectively.
动脉血中气体(即氧气和二氧化碳)的分压是医生判断患者呼吸状况的重要参数。目前在实际操作中,有多种测量这些参数的方法,其中之一是经皮血气监测。该技术是一种常用的非侵入性测量方法,能够快速获得相对准确的结果。在本研究中,采用厚膜技术开发了一种电流型氧传感器,该传感器包括一个加热模块,用于将皮肤表面温度升高到经皮水平。加热模块包括一个加热元件,其温度由温度控制电路调节。使用红外热像仪,分析了加热元件的瞬态和稳态温度分布以及稳定性。还研究了温度对氧传感模块的影响。此外,建立了一个三维理论模型来评估传感器的热响应,并随后与实际原型的结果进行比较。通过该模型,可以简化设计阶段,更轻松有效地生成和改进未来的经皮传感器加热模块。