Matsuoka Yoshie, Yoneda Kozo, Sadahira Chieko, Katsuura Junko, Moriue Tetsuya, Kubota Yasuo
Department of Dermatology, Faculty of Medicine, Kagawa University, Kita-gun, Japan.
J Dermatol. 2006 Nov;33(11):745-52. doi: 10.1111/j.1346-8138.2006.00174.x.
Acne vulgaris significantly affects patients' quality of life (QOL) and their lives in various ways, including social behavior and body dissatisfaction. This may be heightened by acne's typical involvement of the face. We investigated whether the use of skin care and makeup could influence the QOL of affected patients without deteriorating conventional acne treatments. Fifty female patients with acne were recruited for our study. Twenty-five patients were instructed how to use skin care and cosmetics, while 25 patients received no specific instructions from dermatologists. Both groups received conventional topical and/or oral medication for acne during the study period for 4 weeks. Both groups did not show any significant difference in clinical improvement of acne severity. Two validated QOL questionnaires, World Health Organization (WHO)QOL26 and the Dermatology Life Quality Index (DLQI) were administered to all patients at first visit and 4 weeks later. The mean scores of psychological and overall domains in WHOQOL26 for patients with instructions were improved significantly, while only the overall score was significantly improved for patients without instructions. The total mean scores and all domains except work/school in DLQI for patients with instructions were improved significantly, while the total scores and all domains except discomfort for treatment in DLQI were significantly improved for patients without instructions. Thus, instructions on the use of skin care and cosmetics for female acne patients did not deteriorate acne treatment and influenced patients' QOL effectively. We therefore suggest that instructions for using skin care and cosmetics complement conventional medical treatments for acne.
寻常痤疮会以多种方式显著影响患者的生活质量(QOL)及其生活,包括社交行为和身体不满。痤疮通常累及面部可能会加剧这种情况。我们研究了使用护肤品和化妆品是否会影响受影响患者的生活质量,同时又不会降低传统痤疮治疗的效果。我们招募了50名患有痤疮的女性患者进行研究。25名患者接受了如何使用护肤品和化妆品的指导,而25名患者未从皮肤科医生那里得到具体指导。在为期4周的研究期间,两组患者均接受了治疗痤疮的传统外用和/或口服药物治疗。两组患者在痤疮严重程度的临床改善方面均未显示出任何显著差异。在首次就诊时和4周后,对所有患者进行了两份经过验证的生活质量问卷,即世界卫生组织(WHO)QOL26和皮肤病生活质量指数(DLQI)的调查。接受指导的患者在WHOQOL26中心理和总体领域的平均得分有显著提高,而未接受指导的患者只有总体得分有显著提高。接受指导的患者在DLQI中的总平均得分以及除工作/学校领域外的所有领域均有显著提高,而未接受指导的患者在DLQI中的总得分以及除治疗不适领域外的所有领域均有显著提高。因此,针对女性痤疮患者使用护肤品和化妆品的指导不会降低痤疮治疗效果,并且能有效影响患者的生活质量。我们因此建议,关于使用护肤品和化妆品的指导可补充痤疮的传统医学治疗。