欧洲自杀倾向的风险因素:ESEMED研究结果
Risk factors for suicidality in Europe: results from the ESEMED study.
作者信息
Bernal M, Haro J M, Bernert S, Brugha T, de Graaf R, Bruffaerts R, Lépine J P, de Girolamo G, Vilagut G, Gasquet I, Torres J V, Kovess V, Heider D, Neeleman J, Kessler R, Alonso J
机构信息
Sant Joan de Déu-Serveis de Salut Mental, Fundació Sant Joan de Déu, Dr Antoni Pujades 42, 08830, Sant Boi de Llobregat, Spain.
出版信息
J Affect Disord. 2007 Aug;101(1-3):27-34. doi: 10.1016/j.jad.2006.09.018. Epub 2006 Oct 30.
BACKGROUND
Precise knowledge of the epidemiology of suicidality provides necessary information for designing prevention programs. The aims of the present study were to investigate the prevalence and correlates of suicidal ideas and attempts in the general population of Europe.
METHODS
The European Study on the Epidemiology of Mental Disorders (ESEMED) is a cross-sectional household survey carried out in a probability representative sample of non-institutionalised adults (aged 18 years or older) of six European countries (Belgium, France, Germany, Italy, the Netherlands and Spain). The Composite International Diagnostic Interview (CIDI 3.0) was administered to 21,425 individuals.
RESULTS
Lifetime prevalence of suicidal ideation was 7.8% and of suicidal attempts 1.3%. Being women, younger and divorced or widowed were associated with a higher prevalence of suicide ideation and attempts. Psychiatric diagnoses were strongly related to suicidality. Among them, major depressive episode (Rate ratio 2.9 for lifetime ideas and 4.8 for lifetime attempts), dysthymia (RR 2.0 and 1.6), GAD (RR 1.8 and 2.3 for lifetime), PTSD (RR 1.9 and 2.0) and alcohol dependence (RR 1.7 and 2.5) were the most important. Population attributable risks for lifetime suicidal attempt was 28% for major depression.
LIMITATIONS
Information about suicidal ideas and attempts was self reported, psychiatric diagnoses were made using fully structured lay interviews rather than clinician-administered interviews.
CONCLUSIONS
In spite of meaningful country variation in prevalence, risk factors for suicidality are consistent in the European countries. Population prevention programmes should focus on early diagnosis and treatment of major depression and alcohol abuse and in those individuals with recent appearance of suicidal ideas.
背景
对自杀行为流行病学的精确了解为设计预防方案提供了必要信息。本研究的目的是调查欧洲普通人群中自杀观念和自杀未遂的患病率及其相关因素。
方法
欧洲精神障碍流行病学研究(ESEMED)是一项横断面家庭调查,在六个欧洲国家(比利时、法国、德国、意大利、荷兰和西班牙)对非机构化成年人(18岁及以上)进行概率抽样代表性样本调查。对21425人进行了综合国际诊断访谈(CIDI 3.0)。
结果
终生自杀观念患病率为7.8%,自杀未遂患病率为1.3%。女性、年轻人、离婚或丧偶者自杀观念和自杀未遂的患病率较高。精神科诊断与自杀行为密切相关。其中,重度抑郁发作(终生观念的率比为2.9,终生未遂的率比为4.8)、心境恶劣(RR分别为2.0和1.6)、广泛性焦虑障碍(终生RR分别为1.8和2.3)、创伤后应激障碍(RR分别为1.9和2.0)和酒精依赖(RR分别为1.7和2.5)最为重要。重度抑郁症导致的终生自杀未遂人群归因风险为28%。
局限性
自杀观念和自杀未遂的信息为自我报告,精神科诊断采用完全结构化的非专业访谈而非临床医生访谈。
结论
尽管各国的患病率存在显著差异,但欧洲各国自杀行为的危险因素是一致的。人群预防方案应侧重于重度抑郁症和酒精滥用的早期诊断和治疗,以及近期出现自杀观念的个体。