Gasiuk A P, Iagubov A S
Vopr Onkol. 1991;37(2):167-74.
Ontogenetic differentiation of the lung was shown to be subject to determination, divergence and cell differentiation. Delay in determination was followed by proliferation of stem and precursor cells resulting in various types of dysplasia. Disorders of tissue divergence were observed during differentiation whereas various degree of cell differentiation disturbances was registered in moderately and poorly differentiated tumors.
肺的个体发生分化显示出受决定、分化和细胞分化的影响。决定延迟后,干细胞和前体细胞增殖,导致各种类型的发育异常。在分化过程中观察到组织分化紊乱,而在中分化和低分化肿瘤中记录到不同程度的细胞分化障碍。