Guan Yong-Song
Department of Radiology, West China Hospital, Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan Province, China.
World J Gastroenterol. 2006 Nov 7;12(41):6734-5. doi: 10.3748/wjg.v12.i41.6734.
Hepatic veno-occlusive disease (HVOD) is rarely encountered and easily misjudged as Budd-Chiari syndrome. It is often related to stem cell transplantation in recent years. We report a case of HVOD that is related to ingestion of some palatable local dishes. The diagnosis was confirmed by liver biopsy pathology with specific observation of inflammatory changes and fibrosis of venules intima, dilated sinusoids and central veins. Chronic diarrhea is unique for this case as a result of ingesting harmful stuffs. This case demonstrated that supervision and instruction of food recipe and traditional medicine are crucial, and prompt diagnosis, supportive care and specific treatment are essential to decreasing the morbidity and mortality of HVOD.
肝静脉闭塞病(HVOD)很少见,且容易被误诊为布加综合征。近年来,它常与干细胞移植有关。我们报告一例与食用某些可口的当地菜肴有关的HVOD病例。通过肝活检病理检查确诊,观察到小静脉内膜的炎症变化和纤维化、肝血窦扩张及中央静脉扩张等特征性表现。由于摄入有害物质,慢性腹泻是该病例的独特表现。该病例表明,对食谱和传统药物的监管及指导至关重要,而及时诊断、支持治疗和特异性治疗对于降低HVOD的发病率和死亡率必不可少。