Zeiske W, Alpert G, Marin H
Institut für Tierphysiologie und Angewandte Zoologie, Freien Universität Berlin, FRG.
J Basic Clin Physiol Pharmacol. 1990 Jan-Dec;1(1-4):399-404. doi: 10.1515/jbcpp.1990.1.1-4.399.
K(+)-secretion in the midgut of the larval moth, Manduca sexta, was studied by measuring the kinetics of the lumen-directed short-circuit current (Isc) and the conduction noise from basolateral K+ channel block by Ba2+. Hemolymph chloride as well as hypotonicity both stimulate this K+ current (IK). The kinetic nature of the stimulation is, however, different in each case. Analysis of blocker noise supports, to a large degree, the interpretation obtained from kinetics, namely: chloride ions do not act via changes in cell volume but influence ion turnover and channel number.
通过测量幼虫烟草天蛾中肠的腔内向短路电流（Isc）动力学以及Ba2+对基底外侧K+通道阻断产生的传导噪声，研究了K(+)分泌情况。血淋巴氯化物以及低渗性均刺激该K+电流（IK）。然而，每种情况下刺激的动力学性质有所不同。阻断剂噪声分析在很大程度上支持了从动力学得出的解释，即：氯离子并非通过细胞体积变化起作用，而是影响离子周转和通道数量。
