Hjern Anders, Lindberg Lene, Lindblad Frank
National Board of Health and Welfare, 106 30 Stockholm, Sweden.
Br J Psychiatry. 2006 Nov;189:428-32. doi: 10.1192/bjp.bp.105.018820.
Earlier studies have indicated poor long-term outcomes for patients with anorexia nervosa.
To study health and social outcomes of adolescent in-patients with anorexia nervosa in relation to prognostic factors.
A register study based on based on socio-economic and health data was conducted for a national cohort of female residents in Sweden born between 1968 and 1977, including 748 in-patients with anorexia nervosa.
At follow-up 9-14 years after hospital admission, 8.7% of patients with anorexia nervosa had persistent psychiatric health problems demanding hospital care and 21.4% were dependent on society for their main income; the stratified relative risks were 5.8 (95% CI 4.7-7.6) and 2.6 (2.3-3.0) respectively, compared with the general female population. The mortality rate for patients with anorexia nervosa was 1.2% and the stratified risk ratio for maternity was 0.6 (95% CI 0.5-0.7). Long duration of hospital care and psychiatric comorbidity were predictors of persistent psychiatric problems and financial dependency on society.
The outcome in this cohort of adolescent in-patients with anorexia nervosa was considerably better than that reported in previous studies.
早期研究表明神经性厌食症患者的长期预后较差。
研究神经性厌食症青少年住院患者的健康和社会结局及其预后因素。
基于社会经济和健康数据，对瑞典1968年至1977年出生的女性居民全国队列进行登记研究，其中包括748例神经性厌食症住院患者。
在入院9至14年后的随访中，8.7%的神经性厌食症患者存在需要住院治疗的持续性精神健康问题，21.4%的患者主要收入依赖社会救助；与一般女性人群相比，分层相对风险分别为5.8（95%置信区间4.7 - 7.6）和2.6（2.3 - 3.0）。神经性厌食症患者的死亡率为1.2%，生育分层风险比为0.6（95%置信区间0.5 - 0.7）。住院时间长和合并精神疾病是持续性精神问题和对社会经济依赖的预测因素。
该队列中神经性厌食症青少年住院患者的结局比先前研究报告的要好得多。
