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急性胰腺炎的病理生理学、诊断与管理

Pathophysiology, diagnosis and management of acute pancreatitis.

作者信息

Sargent Suzanne

机构信息

Hepatology, Institute of Liver Studies, King's College Hospital, Denmark Hill, London.

出版信息

Br J Nurs. 2006;15(18):999-1005. doi: 10.12968/bjon.2006.15.18.22025.

DOI:10.12968/bjon.2006.15.18.22025
PMID:17077771
Abstract

Pancreatitis is an inflammation of the pancreas that can be either acute or chronic in origin and is caused by a varied range of aetiologies. However, in both types of the disease alcohol use may be a major contributor. In acute pancreatitis the symptoms can range from mild, which resolve within a few days, to severe, which is associated with both multi-organ failure and a high mortality necessitating admission to a high dependency or intensive care unit. As the incidence of acute pancreatitis is increasing it is imperative that nurses are familiar with the causes, underlying pathophysiology, diagnostic tests and the potentially vast range of complications that can occur in acute pancreatitis. This article reviews the current medical and nursing management of this condition.

摘要

胰腺炎是胰腺的一种炎症,其起因可以是急性的或慢性的,由多种病因引起。然而,在这两种类型的疾病中,饮酒都可能是一个主要因素。在急性胰腺炎中,症状范围从几天内即可缓解的轻度症状到与多器官功能衰竭和高死亡率相关的严重症状,后者需要入住高依赖或重症监护病房。由于急性胰腺炎的发病率在上升,护士必须熟悉急性胰腺炎的病因、潜在病理生理学、诊断测试以及可能出现的大量并发症。本文综述了该病目前的医疗和护理管理。

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1
Pathophysiology, diagnosis and management of acute pancreatitis.急性胰腺炎的病理生理学、诊断与管理
Br J Nurs. 2006;15(18):999-1005. doi: 10.12968/bjon.2006.15.18.22025.
2
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A prospective study of the aetiology, severity and outcome of acute pancreatitis in Eastern India.印度东部急性胰腺炎病因、严重程度及预后的前瞻性研究。
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2
Effect of Hypoxia Preconditioned Adipose-Derived Mesenchymal Stem Cell Conditioned Medium on Cerulein-Induced Acute Pancreatitis in Mice.缺氧预处理的脂肪间充质干细胞条件培养基对小鼠雨蛙肽诱导的急性胰腺炎的影响
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Glycyrrhizin down-regulates CCL2 and CXCL2 expression in cerulein-stimulated pancreatic acinar cells.
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Am J Clin Exp Immunol. 2015 Jul 5;4(1):1-6. eCollection 2015.
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Glycyrrhizin attenuates tissue injury and reduces neutrophil accumulation in experimental acute pancreatitis.甘草甜素可减轻实验性急性胰腺炎中的组织损伤并减少中性粒细胞聚集。
Int J Clin Exp Pathol. 2013 Dec 15;7(1):101-9. eCollection 2014.
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Utility of clot formation and lysis assay to monitor global coagulation state of patients with severe acute pancreatitis.凝血和纤溶检测在监测重症急性胰腺炎患者整体凝血状态中的应用。
Dig Dis Sci. 2012 May;57(5):1399-403. doi: 10.1007/s10620-012-2034-6.
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Protective effect of intermedin on myocardial cell in a rat model of severe acute pancreatitis.中介素对重症急性胰腺炎大鼠心肌细胞的保护作用。
Cell Mol Biol Lett. 2011 Sep;16(3):462-76. doi: 10.2478/s11658-011-0020-1. Epub 2011 Jul 18.